Relationship between Odds of RSV disease and the levels of Cord blood antibody titres.

<p>A scatter plot showing the odds of RSV associated hospitalization against maternally transferred RSV specific antibodies (log₂PRNT titres) from cord blood samples of infants (both cases and controls) born in Kilifi, Kenya; 2002–2007. Black symbols denote individual cord titres for all 90 infants.</p

Characteristics of study participants.

<p>Characteristics of study participants.</p

Dynamics of cord titres by time and transmission intensity.

<p>The Red diamond symbols denote individual cord titres by date of birth for RSV A2 strain, Blue diamond symbols denote individual cord titres by date of birth for RSV A Kilifi local strain, Maroon circle markers denote the mean cord titre by quarter (95% CI denoted by Brown whiskers) for RSV A2 strain, Navy blue circle markers denote the mean cord titre by quarter (95% CI denoted by Green whiskers) for RSV A Kilifi local strain. The Grey vertical bars (RSVA) and Orange vertical bars (RSV B) show the number of RSV IFAT positive paediatric severe or very severe pneumonia admissions to Kilifi County Hospital 2002–2005.</p

A box plot of the mean concentration of cord blood titres of cases and controls by age categories.

<p>Differences in the mean concentration of maternally transferred respiratory syncytial virus (RSV) specific antibodies (log₂PRNT titres) from cord blood samples (with P values shown), between cases and controls at age categories in months of first RSV infection; 1–2 and 3–5. Cases were matched to controls in a ratio of 1:2. P values generated using a two sample paired t-test.</p

The estimated rate of decay of RSV specific antibodies from birth to 6 months of life among cases and controls.

<p>The estimated rate of decay of maternally transferred RSV specific antibodies (log₂ transformed PRNT titres) over the first 6 months of life for infants (30 RSV cases and 60 controls) from a birth cohort, Kilifi, Kenya, with best fit linear decay models for samples from cases and controls. Grey symbols denote individual cord titres of cases while black symbols denote individual cord titres of controls.</p