3 research outputs found
Evaluation of diaphragmatic mobility following intra-abdominal sub-diaphragmatic fixation of a double-layered mesh in rats
Evaluation of diaphragmatic mobility following intra-abdominal sub-diaphragmatic fixation of a double-layered mesh in rats
PURPOSE: To evaluate the tissue integration of a double-sided mesh after
fixation in diaphragm and to study the diaphragmatic mobility by
ultrasound.
METHODS: Twenty male Wistar rats were used. The animals were assigned
into two equal groups according to the day of euthanasia. The animals
were anesthetized and a 1.5 x 1.5 cm of double-layer mesh was inserted
between the diaphragm and the liver. For the evaluation of the diaphragm
mobility a sonographic method was used. Measurements on specific
breathing parameters were taking place. Pathological evaluation took
place after the animal's euthanasia.
RESULTS: Extra-hepatic granuloma was not differentiated overtime, (chi
2= 0.04, p>0.05). Neither fibrosis was significantly differentiated,
(chi 2=0.04, p>0.05). Intra-hepatic granuloma was significantly
differentiated overtime, (chi 2= 10.21, p<0.05). Concerning Te
parameter, means were significantly differentiated over time, F (3, 30)
= 5.12, (p<0.01). Ttot parameter, it was differentiated over time, F (3,
8)= 4.79, (p<0.05). IR parameter was also longitudinally differentiated,
F (3, 30)= 3.73, (p<0.05).
CONCLUSION: The measurements suggest a transient malfunction of
diaphragmatic mobility despite the fact that inflammatory reaction,
fibrosis and extra-hepatic granuloma were not significantly
differentiated with the passage of time