PHARMACEUTICO-ANALYTICAL STUDY OF SHODHITA SHILAJATU

In the Pharmaceutical process of different forms of medicines raw material & its quality plays an important role. During ancient time Vaidyas were themselves used to collect the raw materials herbs based on their occurrence and organoleptic characters, i.e., typical taste, texture, smell, color, and there types after selection they utilized them in preparing medicines. Based on their own observations, principles of drug processing and ideal quality of finished product, etc., have been documented by them. The principles were developed based upon the scientific parameters prevailing in those days. Materials and Method: Raw Shilajatu was subjected to Shodhana and Shodhita shilajatu was subjected to analytical study. The required materials for the process were collected from the Pharmacy of BLDEA's AVS Ayurveda Mahavidyalaya pharmacy Vijayapur, analytical lab. Raw drugs were purchased from Dorle and Sons retailer from Kolhapur Maharashtra. Shilajatu shodhana was carried out according to reference mentioned in Rasaratna samuchaya. Analytical tests concern Indian Pharmacopeia methods were followed. Result: Raw Shilajatu took 5 ½ hour to 6hour in Shodhan procedure in both batches. Three days for drying. In analytical tests physical constants like pH ash value, solubility, specific gravity, moisture content etc result values were under normal limit

Observation of pseudogap in MgB2

Pseudogap phase in superconductors continues to be an outstanding puzzle that differentiates unconventional superconductors from the conventional ones (BCS-superconductors). Employing high resolution photoemission spectroscopy on a highly dense conventional superconductor, MgB2, we discover an interesting scenario. While the spectral evolution close to the Fermi energy is commensurate to BCS descriptions as expected, the spectra in the wider energy range reveal emergence of a pseudogap much above the superconducting transition temperature indicating apparent departure from the BCS scenario. The energy scale of the pseudogap is comparable to the energy of E2g phonon mode responsible for superconductivity in MgB2 and the pseudogap can be attributed to the effect of electron-phonon coupling on the electronic structure. These results reveal a scenario of the emergence of the superconducting gap within an electron-phonon coupling induced pseudogap.Comment: 4 figure

Evolution of the Kondo resonance feature and its relationship to spin-orbit coupling across the quantum critical point in Ce2Rh{1-x}CoxSi3

We investigate the evolution of the electronic structure of Ce2Rh{1-x}CoxSi3 as a function of x employing high resolution photoemission spectroscopy. Co substitution at the Rh sites in antiferromagnetic Ce2RhSi3 leads to a transition from an antiferromagnetic system to a Kondo system, Ce2CoSi3 via the Quantum Critical Point (QCP). High resolution photoemission spectra reveal distinct signature of the Kondo resonance feature (KRF) and its spin orbit split component (SOC) in the whole composition range indicating finite Kondo temperature scale at the quantum critical point. We observe that the intensity ratio of the Kondo resonance feature and its spin orbit split component, KRF/SOC gradually increases with the decrease in temperature in the strong hybridization limit. The scenario gets reversed if the Kondo temperature becomes lower than the magnetic ordering temperature. While finite Kondo temperature within the magnetically ordered phase indicates applicability of the spin density wave picture at the approach to QCP, the dominant temperature dependence of the spin-orbit coupled feature suggests importance of spin-orbit interactions in this regime.Comment: 6 figure

Socio-Economic-Political-Cultural Aspects in Malaria Control Programme Implementation in Southern India

Objective. A Socio-economic-political-cultural (SEPC) study was undertaken under the Roll Back Malaria (RBM) initiative to understand the process of programme implementation and how far in the changing malaria context, the broader environment has been understood and programme components have undergone changes. Material and Methods. Two studies were carried out; first in four villages under the primary health unit (PHU) Banavaralu in Tiptur Taluka in September 2002 and the second one in April 2003 in four villages in Chitradurga district, namely, Kappagere, Kellodu in Hosadurga Taluka, and Vani Vilas Puram and Kathrikenhally in Hiriyur Taluka. Focus group discussion and key interviews were adopted to collect the qualitative data. Results. Gender discrimination and lack of empowerment of women came out strongly in social analysis. In the rural elected bodies called Panchayats, the concept of health committees was not known. Health committees as one of the important statutory committees under every Panchayat were nonexistent in reality in these villages. Financial difficulties at Grama Panchayat level and also meager budget allocation for health have led to indifferent attitude of Panchayat members towards health. It was observed that there were generally no specific cultural practices in relation to malaria cure. Cultural and traditional practices in malaria-related issues were not predominant in the community except for some sporadic instances. Conclusion and Recommendation. SEPC study is an important indicator in malaria control programme. It is ultimately the community that takes the major decision directly or indirectly and the health authority must guide them in right direction

The Cosmology of Massless String Modes

We consider the spacetime dynamics of a gas of closed strings in the context of General Relativity in a background of arbitrary spatial dimensions. Our motivation is primarily late time String Gas Cosmology, where such a spacetime picture has to emerge after the dilaton has stabilized. We find that after accounting for the thermodynamics of a gas of strings, only string modes which are massless at the self-dual radius are relevant, and that they lead to a dynamics which is qualitatively different from that induced by the modes usually considered in the literature. In the context of an ansatz with three large spatial dimensions and an arbitrary number of small extra dimensions, we obtain isotropic stabilization of these extra dimensions at the self-dual radius. This stabilization occurs for fixed dilaton, and is induced by the special string states we focus on. The three large dimensions undergo a regular Friedmann-Robertson-Walker expansion. We also show that this framework for late-time cosmology is consistent with observational bounds.Comment: 15 pages, no figures, references added (again

Characterisation and Liberation of Graphite Schist

This paper deals with the characterisation and liberation studies of graphite schist from Shivaganga, Tamilnadu. The graphite flakes are interbanded with quartz and calcite. Secondary calcite veins often traverses graphite flakes and quartz grains. Based on grain counting, frequency curves , comminution followed by flotation tests , the liberation size of graphite is estimated between 150to 90 microns. Therougher concentrate achieved at d&, passing of 145 micron size product contain 35 % FC with 99% recovery.The SFM study reveals the presence of minute inclusions of calcite and quartz within graphite flakes

COMPARATIVE PHYTOCHEMICAL EVALUATION OF ETHNOBOTANICALLY IMPORTANT MEDICINAL PARASITIC HERB: ALECTRA CHITRAKUTENSIS

Objective: Alectra chitrakutensis (M. A. Rau) R. Prasad & R. D. Dixit is a critically endangered and ethnobotanically very important plant. Official drug i.e. dried rhizome of the plant has been reported to be used for treatment of leprosy, tuberculosis, paralysis, oedematous swelling, fevers, intestinal worms and constipation. Besides having high medicinal properties, detail studies on chemical constituents present in the rhizome of this particular species have not been done so far. Thus, in present study efforts were made for evaluation of phytochemical as well as physicochemical analysis of the rhizome collected from six different places of the Chitrakoot region of Madhya Pradesh (M. P.) and Uttar Pradesh (U. P.).Methods: Phytochemical analysis of the rhizome was carried out as per standard protocol given in Ayurvedic Pharmacopoeia of India (API). Separation and qualitative phytochemical screening were done by using an advance technique of High-performance Thin Layer Chromatography (HPTLC).Results: The study revealed the presence of alkaloids, steroids, triterpenoids, flavonoids, glycosides, carbohydrates, starch, saponin, tannins, etc. in the rhizome of the plants, and the study confirmed the chemotaxonomic resemblance among all the collected plant materials.Conclusion: Comparative study of six rhizome samples of A. Chitrakutensis provides authenticity for establishing Pharmacopoeial standardization of drug and evidence of the study proves the chemotaxonomic similarities of official drug.Keywords: Alectra chitrakutensis, Endangered plant, Quality control, Physicochemical, Phytochemical analysis, HPTL