Upgradation of Manual Magnetic Core Drill Machine

This paper deals with the upgradation of existing manual core drill machine. The existing manual core drill machine requires a labor operator every time to drill the hole till the drilling gets completed. So more time is required and accuracy is reduced. So the main aim is to make core drill machine fully automatic. So the automatic part can be developed by developing some of the part related to current sensing and controlling, depth sensing using encoder, no load position sensing , enrolling the required depth through the keypad and operating it with the stepper motor

Artificial Neural Network Based Automatic Number Plate Recognition System

This paper deals with Automatic Number Plate Recognition (ANPR) using Artificial Neural Network. The ANPR system includes steps like pre-processing, localization, character segmentation and character recognition. The developed system first detects the vehicle and then captures the vehicle image. The captured image is pre-processed in order to enhance it for further processing. In localization the license plate region is located and cropped from the complete image. In character segmentation images of individual alpha-numeric characters are extracted from the localized plate. In this paper, we proposed Neural Network based character recognition. Scaled Conjugate Gradient Backpropogation algorithm is used for training the neural network. This system is implemented in MATLAB R2014b

Role of Drug Repurposing in Cancer Treatment and Liposomal Approach of Drug Targeting

Cancer is the leading cause of death, and incidences are increasing significantly and patients suffering from it desperately need a complete cure from it. The science of using an already-invented drug that has been approved by the FDA for a new application is known as “drug repurposing.” Currently, scientists are drawn to drug repositioning science in order to investigate existing drugs for newer therapeutic uses and cancer treatment. Because of their unique ability to target cancer cells, recently repurposed drugs and the liposomal approach are effective in the treatment of cancer. Liposomes are nanovesicles that are drastically flexible, rapidly penetrate deeper layers of cells, and enhance intracellular uptake. More importantly, liposomes are biocompatible, biodegradable; entrap both hydrophobic and hydrophilic drugs. This chapter summarizes various approaches to drug repurposing, as well as drug repurposing methods, advantages and limitations of drug repurposing, and a liposomal approach to using repurposed drugs in cancer targeting. This chapter also summarizes liposomal structure, drug loading, and the mechanism of liposomes in targeted cancer treatment. The lipid-based liposomal approach is emerging as a powerful technique for improving drug solubility, bioavailability, reducing side effects, and improving the therapeutic efficacy of repurposed drugs for cancer treatment

Comparison and Consensus Guidelines for Delineation of Clinical Target Volume for CT- and MR-Based Brachytherapy in Locally Advanced Cervical Cancer

To create and compare consensus clinical target volume (CTV) contours for computed tomography (CT) and 3 Tesla (3T) magnetic resonance (MR) image-based cervical-cancer brachytherap

Prevention of recurrence and relapse of tinea incognito W.S.R. to Dadru

Introduction: Fungal infections are the most common infection of skin in India. Recurrence and relapse are very common. Incomplete treatment and use of steroid is responsible for resistant Tinea incognito. Main Clinical Finding: A female patient of 23-year-old had erythematous papulo-vesicular lesions over the right underarm and inguinal region from the last 1 year. History of temporary relief due to modern medicine with relapse was observed. Striae marks were evident over thighs indicating skin atrophy. Diagnosis: Patient was diagnosed with Tinea incognito (Ayurvedic diagnosis Dadru with Dooshivisha as a causative factor). Interventions: Patient was successfully managed with Dooshivishahara and Rakta Prasadak Chikitsa. Outcome: Improvement was evident after 3 weeks of therapy. No recurrence was reported till date. Conclusions: Ayurvedic approach to Tinea incognito not only helps to reduce relapse and recurrence but also physical discomfort and financial burden on patient

Potential of Vitex negundo roots in the treatment of ulcerative colitis in mice

Objective: The present work was undertaken to validate its folk use in the treatment of ulcerative colitis (UC) by using the method of acetic acid-induced colitis in mice