Obstetric-associated lower urinary tract injuries: a single-center study

Background: Urinary tract injury is a known complication of obstetric and gynecologic surgery. Intraoperative identification of injury permits prompt repair and potentially lessens postoperative sequelae including patient morbidity and cost. Delayed diagnosis of urinary tract injuries can result in physical complications beyond the site of the injury, such as genitourinary fistula formation, renal injury, sepsis, death, and psychosocial dysfunction.Methods: We describe the management of 27 patients with such injuries, including their demographic profile, associated factors, and complications at a tertiary institution in a retrospective study from February 2013 to March 2021.Results: Bladder injuries were the most common (81.5%), mostly occurring during emergency cesarean delivery, with previous cesarean delivery and adhesions being risk factors. A primary repair was attempted at the referring institution in 18.5% of cases. Repair at the tertiary institution was mostly performed by consultants (66.7%).Conclusions: Early recognition and primary repair are associated with fewer complications

In vitro Test of Aspirin, Conventional Immediate Release vs. Sustained Release Tablet

Sustained-release tablets have emerged as a crucial advancement in pharmaceutical technology, offering improved drug delivery and therapeutic outcomes compared to conventional immediate-release formulations. This abstract highlights the sustained-release tablet's key attributes and significance in enhancing drug performance and patient compliance. Comparative studies between aspirin sustained-release and conventional-release tablets provide insights into their differing pharmacokinetic profiles and clinical impacts. Sustained-release formulations may offer prolonged pain relief, more stable antiplatelet effects, and reduced risk of gastrointestinal irritation compared to immediate-release tablets. Nevertheless, immediate-release aspirin might retain advantages in situations requiring rapid pain relief or acute antiplatelet effects.</p