E3 : Keyphrase based News Event Exploration Engine

This paper presents a novel system E3 for extracting keyphrases from news content for the purpose of offering the news audience a broad overview of news events, with especially high content volume. Given an input query, E3 extracts keyphrases and enrich them by tagging, ranking and finding role for frequently associated keyphrases. Also, E3 finds the novelty and activeness of keyphrases using news publication date, to identify the most interesting and informative keyphrases

Does Race Play a Role in the Robustness of the Flu Vaccine Response in Obese Women?

Obesity prevalence has increased drastically over the last couple of decades. Obesity increases an individual’s risk of health complications such as cardiovascular disease, hypertension, and other chronic conditions. Obesity has been related to an increased susceptibility to infection and complications from the influenza virus. In the present study, the immune responses to the influenza vaccine between races in obese women will be compared by determining the percent increases in immunoglobulin G subtype levels from pre to post vaccination. To accomplish this, serum was collected from study participants and tested for antibody levels pre and post vaccination using an indirect enzyme-linked immunosorbent assay. For IgG1 and IgG3, average percent increases pre to post vaccination displayed no difference between African American women and Caucasian women. IgG2 was not present in detectable levels in the population studied and was not able to be analyzed. For IgG4, the average percent increase pre to post vaccination displayed a statistically significant difference between African American women and Caucasian women. African Americans had a significantly lower average percent increase in IgG4 pre to post vaccination compared to Caucasians. This suggests that there may be lower levels of IgG4 in African American women in general compared to Caucasian women. Future studies should be conducted to further investigate these relationships.Bachelor of Science in Public Healt

CoCast - SLR

We are currently living in a world surrounded by technology, making us very dependent on the little nitty gritty way of accomplishing tasks efficiently. Being mindful of the of the changes that are occurring upon us, we are compelled to helping where possible. Personally, Sheridan College pilots their very own campus radio station – Sheridan Life Radio (SLR) a member of the National Campus and Community Radio Association, whose main aim is to bring a little bit of everything to the table covering special occasions such as Canadian upcoming holidays, Valentine’s Day, Mother’s Day to motivational and inspirational podcasts. SLR primarily doesn’t only produce content for the college but for podcasting platforms such as Spotify, Google Podcasts and Apple Podcast. Hence, keeping in mind of the wide variety of topics that the SLR tackles, the most troublesome one happens to be the management of podcasts. Where the mode of operation for them currently is to have individuals chase producing – the act of finding guests, stories and angles and collaborative podcasting process. This process can be nerve-wreaking and frustrating. To help SLR overcome this problem a proposed solution is to have procuring audio clips to one stop location for the clip gathering cutting the stress and effect of people personally being out and about in the field. Since the proposed solution aims to make the way of operation smarted and less stressful for the SLR team it is called Co-Cast

RATIO SPECTRA DERIVATIVE UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF KETOROLAC TROMETHAMINE AND PHENYLEPHRINE HYDROCHLORIDE IN IMMEDIATE RELEASE TABLET

Objective: To develop and validate robust, accurate and precise UV spectrophotometric method for determination of Ketorolac Tromethamine and Phenylephrine Hydrochloride.Methods: Ratio spectra derivative method was developed using water as solvent. The developed method was validated as per International Conference on Harmonization (ICH) guidelines.Results: Linearity of the developed method was 0.9958 and 0.9987 in the range of 4-20 ppm and 12-60 ppm for Ketorolac Tromethamine and Phenylephrine Hydrochloride respectively. % Relative standard deviation (RSD) was found to be less than 2 for Intraday precision and Intermediate precision. % recovery was found to be 98.5–100.27 % and 98.38–101.99 % for Ketorolac Tromethamine and Phenylephrine Hydrochloride respectively.Conclusion: A robust, accurate and precise UV spectrophotometric method was developed and validated as per ICH guidelines.Â

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF TAPENTADOL HCL, ACECLOFENAC AND PARACETAMOL IN TERNARY MIXTURE

Objective: To develop a accurate, precise and specific RP-HPLC method for simultaneous estimation of Tapentadol HCl (TAP), Aceclofenac (ACE) and Paracetamol (PCM) in its laboratory synthetic mixture.Methods: The optimized method uses C8 Thermo quest, hypersil division, 250*4.60 mm; 5 μ column, mobile phase consisting of phosphate buffer (pH 3) and acetonitrile in the ratio of 40:60, flow rate 0.8 ml/min. The detection wavelength was set at 217 nm.Results: The developed method resulted Paracetamol, Tapentadol HCl and Aceclofenac in eluting at 4.008 min 4.595 min and 6.073 min respectively. Linearity was observed over the concentration range of 52-130 µg/ml for PCM, 16-40 µg/ml forACE and 12-30 µg/ml forTAP. The percentage recovery was found to be in the range of 98-102% at three different levels of a standard addition. The precision (intra-day, inter-day) of the method was within the limit (RSD<2%).Conclusion: The proposed method was found to be accurate, precise, reproducible and specific and it can be used for qualitative and quantitative determination of Tapentadol HCl, Aceclofenac and Paracetamol in their combined dosage form in the pharmaceutical industry.Â

Study of therapeutic role of yoga (Hathyoga) on lipid profile in dyslipidemic individuals of Ahmedabad city

333-338Abnormal lipid profile is a common problem among hypertensive as well as working individuals. The rate of mortality is increasing day-by-day due to cardiovascular problems which occurs due to dyslipidemia. The aim of the present study was to assess the therapeutic role of yoga on lipid profile in Ahmedabad population. Total 50 normal healthy control and 50 individuals with dyslipidemia aged >20 years were enrolled for the present study. They were divided into two groups. Individuals in Group-1 were normal healthy, whereas individuals in Group-2 were dyslipidemics. All participants were subjected to yoga practices (Hathyogic practices - Pranayama, yoga postures and meditation) for the various intervals of 0, 3, 6, 9, and 12 months. Serum lipid profile was estimated for all individuals at different intervals. Before beginning the yoga intervention i.e., at 0 month the levels of Total Cholesterol, Total Triglycerides, LDL-cholesterol and VLDL-cholesterol were significantly high, whereas HDL-cholesterol levels were significantly low. After completion of 12 months yoga intervention a significant reduction was observed in Total Cholesterol, Total Triglycerides, LDL-cholesterol and VLDL-cholesterol as well as a significant elevation of HDL-cholesterol was observed. Yoga (Hathyoga) can be a new added adjuvant and cost effective therapy for the patients with abnormal lipid profile

Comparative study of efficacy and safety of intravenous ferric carboxy maltose versus iron sucrose in treatment of postpartum iron deficiency anemia

Background: As postpartum iron deficiency anemia is observed in about 65% of women in India, it is the major contributing factor and indirect cause of maternal death. Postpartum anemia may lead to postpartum depression, stress, anxiety and cognitive impairment. Adequate treatment of anemia in postpartum period will have improved life quality in women in child bearing age so this study was designed with the objective to compare the safety and efficacy of intravenous FCM versus iron sucrose in treatment of postpartum iron deficiency anemia.Methods: It was a prospective observational study of postpartum women (within 10 days of delivery) with iron deficiency anemia (7-9 gm%) who delivered in LG hospital, Ahmedabad. A sample size of 215 women was estimated based on prevalence of anemia which is 65% among postpartum women in India including dropout rate of 10% which were further divided into 2 groups. Group 1: iron sucrose group, Group 2: ferric carboxy maltose group.Results: FCM has greater rise in Hb, less side effects, and easy administration of dose as compared to iron sucrose. The rise in Hb with FCM as compared to iron sucrose is (4.6 versus 3.5 respectively).Conclusions: FCM has more safety and efficacy as compared to iron sucrose in treatment of postpartum iron deficiency anemia

BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF HCG (HUMAN CHORIONIC GONADOTROPIN)

Objective: To develop and validate simple, rapid, specific, accurate and precise bioanalytical method for determination of the HCG (Human Chorionic Gonadotropin) by RP-HPLC method by using human urine.Methods: The chromatographic separation was performed using Phenom enex C18 (250 x 4.6 mm, 5μ, 300 °A) column. Mobile phase composed of sodium phosphate buffer (pH 7.0, 0.05M) and acetonitrile (87.5:12.5 % v/v) at a flow rate of 1 ml/min. Detection was carried out using UV detector at 215 nm. Bovine serum albumin (BSA) was used as an internal standard (ISTD) and extraction was carried out using protein precipitation method. The method was validated as per USFDA guidelines.Results: The method was linear over the concentration range of 0.37 to 48.4 µg/ml. and correlation coefficient (R2) was found to be 0.9983 and the Lower limit of quantitation (LLOQ) was 0.37 µg/ml. Recovery was found more than 94.0% for HCG. The % CV for interday and intraday precision was found to be less than Ë‚1%.Conclusion: A simple, rapid, specific, accurate and precise analytical method was developed and validated by using human urine.Â

The effect of habitat on constitutive levels and inducibility of leaf phenolics in American Beech (Fagus grandifolia)

General EcologyPlants use chemical defenses to ward off herbivory. Phenolics, a carbon-based chemical defense, are present in all woody plants. There are many biotic and abiotic factors that can affect the levels of phenolics present in plant tissue. Two factors that can affect phenolic levels are carbon and nitrogen availability. Often these factors vary with habitats. Glacial moraines often have mesic, nitrogen rich soil. Glacial outwash plains often have xeric soil with less nitrogen. To see the effects of carbon and nitrogen availability on constitutive levels and inducibility of phenolics, we tested constitutive levels and inducibility of phenolics in American Beech (Fagus grandifolia) in both habitats. Trees from the outwash plain had higher constitutive levels of phenolics. Though both sites induced phenolics in response to leaf damage, neither site produced a significantly greater amount.http://deepblue.lib.umich.edu/bitstream/2027.42/57730/1/Zrust_Cardone_Yee_ Patel_2007.pd