1 research outputs found
DUbbing language-therapy CINEma-based in aphasia post-stroke (DULCINEA): study protocol for a randomized crossover pilot trial
Communication is one of the most important predictors of social reintegration after stroke.
Approximately 15–42% of stroke survivors experience post-stroke aphasia. Helping people recover from aphasia is
one of the research priorities after a stroke. Our aim is to develop and validate a new therapy integrating dubbing
techniques to improve functional communication.
Methods: The research project is structured as three work packages (WP). WP1: development of the dubbed
language cinema-based therapy: Two research assistants (a speech therapist and a dubbing actor) will select the
clips, mute specific words/sentences in progressive speech difficulty, and guide patients to dub them across
sessions. Words to be dubbed will be those considered to be functionally meaningful by a representative sample of
aphasic patients and relatives through an online survey. WP2: a randomized, crossover, interventional pilot study
with the inclusion of 54 patients with post-stroke non-fluent aphasia. Patients will be treated individually in 40-min
sessions twice per week for 8 weeks. Primary outcomes will be significant pre/post differences in scores in the
Communicative Activity Log (CAL) questionnaire and Boston Diagnostic Aphasia Examination (BDAE) administered
by a psychologist blinded to the patients’ clinical characteristics. Secondary outcomes: General Health Questionnaire
(GHQ)-12, Stroke Aphasia Quality of Life Scale (SAQOL-39), Western Aphasia Battery Revised (WAB-R), and the Stroke
Aphasic Depression Questionnaire (SADQ10). WP3: educational activities and dissemination of results. WP3 includes
educational activities to improve public knowledge of aphasia and dissemination of the results, with the
participation of the Spanish patients’ association Afasia Activa.
Discussion: This pilot clinical trial will explore the efficacy of a new therapeutic tool based on dubbing techniques
and computer technology to improve functional communication of patients suffering from post-stroke aphasia with
the use of standardized test assessmentThis study is promoted by Blanca Fuentes and the Research Foundation of
La Paz University Hospital, which hosts a research consortium joined by the
Department of Neurology at La Paz University Hospital, the Department of
Psychology at Comillas Pontifical University, and the patients’ association
Afasia Activa. This project has received funding from “la Caixa” Banking
Foundation under the project code HR18-00026. Funder is not involved in
any of the following processes: design of the trial, data collection, analysis, or
interpretation of data nor than in writing the manuscrip