Spectral characteristics of waves and particles in the model of cyclotron wave-particle interactions near plasmapause

International audienceFurther analysis of energetic electron precipitation at the evening sector of magnetosphere is performed. In the framework of the quantitative model of cyclotron wave-particle interactions developed in the previous Pasmanik et al. paper, the case of finite spread over energies of initial energetic electron distribution is studied. The solution for distribution function of energetic electron is found. The energetic spectrum of trapped and precipitating electrons and whistler wave spectrum are analysed

Collapse of Incoherent Light Beams in Inertial Bulk Kerr Media

We use the coherent density function theory to show that partially coherent beams are unstable and may collapse in inertial bulk Kerr media. The threshold power for collapse, and its dependence on the degree of coherence, is found analytically and checked numerically. The internal dynamics of the walk-off modes is illustrated for collapsing and diffracting partially coherent beams

Effects of IKAP/hELP1 Deficiency on Gene Expression in Differentiating Neuroblastoma Cells: Implications for Familial Dysautonomia

Familial dysautonomia (FD) is a developmental neuropathy of the sensory and autonomous nervous systems. The IKBKAP gene, encoding the IKAP/hELP1 subunit of the RNA polymerase II Elongator complex is mutated in FD patients, leading to a tissue-specific mis-splicing of the gene and to the absence of the protein in neuronal tissues. To elucidate the function of IKAP/hELP1 in the development of neuronal cells, we have downregulated IKBKAP expression in SHSY5Y cells, a neuroblastoma cell line of a neural crest origin. We have previously shown that these cells exhibit abnormal cell adhesion when allowed to differentiate under defined culture conditions on laminin substratum. Here, we report results of a microarray expression analysis of IKAP/hELP1 downregulated cells that were grown on laminin under differentiation or non-differentiation growth conditions. It is shown that under non-differentiation growth conditions, IKAP/hELP1 downregulation affects genes important for early developmental stages of the nervous system, including cell signaling, cell adhesion and neural crest migration. IKAP/hELP1 downregulation during differentiation affects the expression of genes that play a role in late neuronal development, in axonal projection and synapse formation and function. We also show that IKAP/hELP1 deficiency affects the expression of genes involved in calcium metabolism before and after differentiation of the neuroblastoma cells. Hence, our data support IKAP/hELP1 importance in the development and function of neuronal cells and contribute to the understanding of the FD phenotype

Spectral characteristics of waves and particles in the model of cyclotron wave-particle interactions near plasmapause

Further analysis of energetic electron precipitation at the evening sector of magnetosphere is performed. In the framework of the quantitative model of cyclotron wave-particle interactions developed in the previous Pasmanik et al. paper, the case of finite spread over energies of initial energetic electron distribution is studied. The solution for distribution function of energetic electron is found. The energetic spectrum of trapped and precipitating electrons and whistler wave spectrum are analysed.Key words. Magnetospheric physics (energetic particles · precipitating; energetic particles · trapped); · Space plasma physics (wave-particle interactions)

Dispersion properties of ducted whistlers, generated by lightning discharge

Whistler-mode wave propagation in magnetospheric ducts of enhanced cold plasma density is studied. The case of the arbitrary ratio of the duct radius to the whistler wavelength is considered, where the ray-tracing method is not applicable. The set of duct eigenmodes and their spatial structure are analysed and dependencies of eigenmode propagation properties on the duct characteristics are studied. Special attention is paid to the analysis of the group delay time of one-hop propagation of the whistler wave packet along the duct. We found that, in contrast to the case of a wide duct, the group delay time in a rather narrow duct decreases as the eigenmode number increases. The results obtained are suggested for an explanation of some types of multi-component whistler signals