TREATMENT WITH APHERESIS

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NUTRITIONAL REGIMEN OF NEW THERAPEUTIC STRATEGIES IN CHRONIC RENAL FAILURE

Nowadays the number of the patients with chronic renal failure and the syndrome of end-stage renal disease permanently increases. New dietary regimens are necessary to improve the status of the patients with severe kidney diseases. Nutrition plays an essential role in the contemporary approach to the management of the patients with renal failure. Low-protein diet delays the progression of the renal failure. The meta-analysis of the effect of dietary protein restriction on the course of diabetic and non-diabetic renal diseases outlines the importance of the adequate correction of the uremic syndrome and the absence of side effects of this nutritional regimen. The development of appropriate diet therapy to be administered at the predialytic stage of the disease could prevent or at least delay the progression of chronic renal failure and, in this way, it represents a challenge for the nephrologists and hope for the patients

KALLIKREIN-KININ SYSTEM (KKS) AND ANGIOTENSIN CONVERTING ENZYME ACTIVITY (ACE) IN PATIENTS ON PERIODIC HA•MODIALYSIS (PHD) TREATED WITH RECOMBINANT HUMAN ERYTHROPOIETIN (rhEPO)

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USE OF INTENSIVE METHODS FOR TREATMENT OF RENAL DISEASES

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Bone turnover markers in sheep and goat: a review of the scientific literature

Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants.José Arthur de A. Camassa acknowledges to the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brazil, for his PhD scholarship 202248/2015-1.info:eu-repo/semantics/publishedVersio

Robert Koch „ловецът на микроби“ 175 години от рождението на учения

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