PPI-network analysis.

<p>Significant PPI-network (p-value <0.0001) containing 17 proteins associated with disc degeneration (red circles) and 76 interaction partners (white circles).</p

Study flow diagram.

<p>Study flow diagram.</p

Details of meta-analyses in the identified reports of genes with a moderate level of evidence.

<p>CI = 95% confidence interval, N = total number of individuals in the study. Dash (−) indicates missing information in the report.</p