Paraoxonase gene polymorphisms and haplotype analysis in a stroke population

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Long‑term risk of stroke following percutaneous coronary intervention : can we predict the future and can we change it?

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Lemon Juice as a Natural Catalyse for Synthesis of Shiff’s base: A Green Chemistry Approach

The advantages of the use of natural catalysts are eco-friendly, inexpensive, high yields, nonhazardous and short reaction times. The utilization of green chemistry techniques is the elimination of solvents during chemical processes or the replacement of hazardous solvents with environmentally friendly solvents. Green chemistry has used for the synthesis of Schiff bases. Synthesis of Schiff base is carried out the mixture of aldehyde (or ketone) and amine in organic medium with or without an acid catalyst. He presents study Uses Lemon juice as a natural and eco-friendly catalyst in the green chemistry investigated. The synthesized product was characterized by its physical properties, melting point, TLC and then subjected to the in vitro antibacterial activities against gram-positive and gram-negative strains of microbes

Using of Naproxen drug for novel synthesis of 4-thiazolidinone derivatives and application of these drugs as no steroidal anti-inflammatory drug (NSAIDs) and as anti-epileptic agent

Non-steroidal anti-inflammatory drugs (NSAIDs) are now one of the most frequent drugs used in treatment of pain, inflammation and fever. In this study the aim is the synthesis of derivatives of 4-Tiazolidinon from naproxen with the possible anti-pain effects, and the main purpose of providing these derivatives is to achieve a compound with more anti-pain power and less side effects in comparison with applied drugs in clinics. Synthesis of these derivatives is done on chloride in presence of a group of new liquids like recyclable ionic liquids choline chloride, which the main advantages of these ionic liquids are the cheapness, availability, being non-toxic, and easy recyclability. This reaction was done in four stages. All the structures were verified by using data of spectrum testing, 1H-NMR, FT-IR

Association of RS4784227-casc16 (Loc643714 locus) and RS4782447-ACSF3 polymorphisms and their association with breast cancer risk among iranian population

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Secondary findings from whole-exome sequencing data in families with familial combined hyperlipidemia (FCHL)

Acknowledgements The grant of this study was paid by Mashhad University of Medical Sciences, Mashhad, Iran. Funding This study was funded by Mashhad University of Medical Sciences.Peer reviewedPublisher PD

Country-level determinants of the severity of the first global wave of the COVID-19 pandemic : an ecological study

Acknowledgements We would like to thank Dr Kathryn Martin, who provided valuable advice in study design. Funding This work was supported by the Aberdeen Clinical Academic Training Scheme.Peer reviewedPublisher PD

An ecological study assessing the relationship between Public Health Policies and Severity of the COVID-19 Pandemic

Funding: This research received no external funding.Peer reviewedPublisher PD

Genetic determinants of premature menopause in A Mashhad population cohort

Funding Information: This work was supported by a grant from the Vice Chancellor for Research at Mashhad University of Medical Sciences and this was a part of the Ph.D. student dissertation (no. 971084). The authors have no conflict of interest to disclose.Peer reviewedPublisher PD

A method for improving the efficiency of DNA extraction from clotted blood samples

Funding information: This study was supported by a grant from the Research Council of the Mashhad University of Medical Sciences (Grant No: 931680). The authors would like to thank Dr. Hossein Eshghi at Department of Chemistry, Faculty of Science, the Ferdowsi University of Mashhad for his assistance in the experiment and Mohammad Sadegh Khorami who contributed to this study. We are also particularly grateful to the Research Council of the Mashhad University of Medical Sciences (MUMS) for the financial support of this studyPeer reviewedPublisher PD