Main clinical and epidemiological characteristics of reported cases of transfusion-transmitted arboviruses.

Main clinical and epidemiological characteristics of reported cases of transfusion-transmitted arboviruses.</p

Flow chart for the process of selecting records describing other mechanisms of direct transmission.

(DOCX)</p

Arboviruses that could pose a threat to transfusion safety due to direct non-vector related transmission mechanisms.

Arboviruses that could pose a threat to transfusion safety due to direct non-vector related transmission mechanisms.</p

Flow chart on selection of case studies of transfusion-transmitted arboviruses.

(DOCX)</p

PICOT research question.

(DOCX)</p

Main reported clinical and epidemiological characteristics of transfusion-transmitted dengue virus.

Main reported clinical and epidemiological characteristics of transfusion-transmitted dengue virus.</p

Transfusion-transmitted West Nile virus cases.

Transfusion-transmitted West Nile virus cases.</p

S1 PRISMA Checklist -

(DOCX)</p

Transfusion-transmitted dengue virus cases.

Transfusion-transmitted dengue virus cases.</p

Main reported clinical and epidemiological characteristics of transfusion-transmitted West Nile virus Of the reported transfusion transmitted cases related to dengue virus, 50% (N = 9; 95% CI: 26.9–73.1%) originated from Brazil.

Transfusion of red blood cells was the main route of transmission described (N = 8, 44.4%; 95% CI: 21.5–67.4%). Symptoms were reported for 61.1% (N = 11; 95% CI: 38.6–83.6%) of recipients. None of the selected cases of transfusion transmission of dengue virus were reported as fatal. In 38.9% (N = 7; 95% CI: 16.4–61.4%) of cases, the serotype involved was DENV-4. Fig 5 presents the main reported clinical and epidemiological characteristics of cases of transfusion transmission of dengue virus.</p