Predictive factors for adherence in patients aged ≥ 75.

<p>OHS: obesity hypoventilation syndrome, MMSE: mini mental state examination</p><p>Predictive factors for adherence in patients aged ≥ 75.</p

Study population at baseline.

<p>Values expressed as mean (SD) or n (%). BMI = body mass index, LTOT = long-term oxygen therapy, OHS = obesity hypoventilation syndrome, ICU = intensive care unit, FEV₁ = forced expiratory volume in 1 s, FVC = forced vital capacity, IPAP = inspiratory partial airway pressure, EPAP = expiratory partial airway pressure, Min RR = minimal respiratory rate</p><p>Study population at baseline.</p

Comparison of the impact of NIV on HRQL evaluated by SF-36 in patients aged < 75 years or ≥ 75 years.

<p>Values expressed as mean (SD).</p><p>Δ: variation between baseline and 6 months</p><p>*p value < 0.05</p><p>^‡p value for comparison of Δ between ≥ 75 and < 75</p><p>PCS: physical component summary, MCS: mental component summary</p><p>Comparison of the impact of NIV on HRQL evaluated by SF-36 in patients aged < 75 years or ≥ 75 years.</p

Comparison of NIV efficacy at 6 months in patients aged < 75 years or ≥ 75 years.

<p>Δ: variation between baseline and 6 months</p><p>*p value < 0.05</p><p>^†percentage of patients with initial Epworth scale score over 10</p><p>^§ percentage of patients with initial Pittsburgh sleep quality index over 7</p><p>^‡p value for comparison of Δ between ≥ 75 and < 75</p><p>ESS: Epworth scale score, PSQI: Pittsburgh sleep quality index</p><p>Comparison of NIV efficacy at 6 months in patients aged < 75 years or ≥ 75 years.</p

Multivariate adjusted Odds Ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep duration in the whole obstructive sleep apnea (OSA) group and in the 2 categories of OSA severity.

<p>SDB, sleep-disordered breathing.</p><p>OR were adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, time in bed, and study site.</p><p>* p<0.05.</p><p>**p<0.01.</p><p>Multivariate adjusted Odds Ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep duration in the whole obstructive sleep apnea (OSA) group and in the 2 categories of OSA severity.</p

Multivariate adjusted odds ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep-disordered breathing or sleep duration.

<p>OSA, obstructive sleep apnea.</p><p>Model 1 included OSA severity or sleep duration adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, time in bed, and study site.</p><p>Model 2 included OSA severity or sleep duration adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, sleep latency, and study site.</p><p>Model 3 included OSA severity or sleep duration adjusted for age, gender, obesity, diabetes, depression, current smoking, use of thyroid hormones, excessive daytime sleepiness, poor sleep, time spent in slow wave sleep, overall arousal index, wake time after sleep onset, and study site.</p><p>Adjusted OR were all statistically significant with p value <0.01</p>†<p>Tested by the Cochrane-Armitage trend test.</p><p>Multivariate adjusted odds ratio (OR) (95% confidence interval [CI]) for hypertension associated with sleep-disordered breathing or sleep duration.</p

Characteristics of the study population.

<p>Data are expressed as mean (SD) or percentages.</p><p>HTN, hypertension; BMI, body mass index; EDS, excessive daytime sleepiness; WASO, wake time after sleep onset; REM, rapid eye movement; SW, slow wave.</p><p>Characteristics of the study population.</p