Restoration of brain dha levels in young-deficient rat is better with 1.5% ala dairy fat blend compared to 1.5% ala vegetable blend

International audienc

Protective effect of dairy fat on brain dha levels of young rats born from ala-deficient or ala-rich mothers

International audienc

Protective effect of dairy fat on brain dha levels of young rats born from ala-deficient or ala-rich mothers

International audienc

Restoration of brain dha levels in young-deficient rat is better with 1.5% ala dairy fat blend compared to 1.5% ala vegetable blend

International audienc

Impact de la loi Sapin dans les transports collectifs urbains : loi 93-122 du 29 janvier 1993 relative à la prévention de la corruption et à la transparence de la vie économique et des procédures publiques

22 AO sur les 36 sollicitées ont répondu au questionnaire. Les points essentiels qui ressortent sont les suivants :- La durée moyenne d’une procédure est de 8,7 mois.- A l’appel à candidature, on trouve généralement 4 nationaux pour un local, l’anglais Southern Vectis confirmant cette année son intérêt pour les dossiers proposés.- On constate un nombre de désistements croissant par rapport à l’année antérieure, après la déclaration de candidature, 8 AO ne recevant qu’une seule offre.- 7 réseaux ont changé d’exploitant, l’implantation des groupes nationaux se renforçant.- 7 contrats ont changé de nature, au détriment des gérances.- La qualité du service apparaît comme un point fort de la rédaction des nouveaux contrats.- Malgré sa lourdeur, la procédure est majoritairement appréciée par les AO et les recours sont peu fréquents

Soluble Milk Protein Supplementation with Moderate Physical Activity Improves Locomotion Function in Aging Rats

International audienceAging is associated with a loss of muscle mass and functional capacity. Present study was designed to compare the impact of specific dairy proteins on muscular function with or without a low-intensity physical activity program on a treadmill in an aged rat model. We investigated the effects of nutritional supplementation, five days a week over a 2-month period with a slow digestible protein, casein or fast digestible proteins, whey or soluble milk protein, on strength and locomotor parameters in sedentary or active aged Wistar RjHan rats (17-19 months of age). An extensive gait analysis was performed before and after protein supplementation. After two months of protein administration and activity program, muscle force was evaluated using a grip test, spontaneous activity using an open-field and muscular mass by specific muscle sampling. When aged rats were supplemented with proteins without exercise, only minor effects of different diets on muscle mass and locomotion were observed: higher muscle mass in the casein group and improvement of stride frequencies with soluble milk protein. By contrast, supplementation with soluble milk protein just after physical activity was more effective at improving overall skeletal muscle function in old rats compared to casein. For active old rats supplemented with soluble milk protein, an increase in locomotor activity in the open field and an enhancement of static and dynamic gait parameters compared to active groups supplemented with casein or whey were observed without any differences in muscle mass and forelimb strength. These results suggest that consumption of soluble milk protein as a bolus immediately after a low intensity physical activity may be a suitable nutritional intervention to prevent decline in locomotion in aged rats and strengthen the interest to analyze the longitudinal aspect of locomotion in aged rodents

Impact de la loi Sapin dans les transports collectifs urbains : loi 93-122 du 29 janvier 1993 relative à la prévention de la corruption et à la transparence de la vie économique et des procédures publiques

22 AO sur les 36 sollicitées ont répondu au questionnaire. Les points essentiels qui ressortent sont les suivants :- La durée moyenne d’une procédure est de 8,7 mois.- A l’appel à candidature, on trouve généralement 4 nationaux pour un local, l’anglais Southern Vectis confirmant cette année son intérêt pour les dossiers proposés.- On constate un nombre de désistements croissant par rapport à l’année antérieure, après la déclaration de candidature, 8 AO ne recevant qu’une seule offre.- 7 réseaux ont changé d’exploitant, l’implantation des groupes nationaux se renforçant.- 7 contrats ont changé de nature, au détriment des gérances.- La qualité du service apparaît comme un point fort de la rédaction des nouveaux contrats.- Malgré sa lourdeur, la procédure est majoritairement appréciée par les AO et les recours sont peu fréquents

Ripened dairy products differentially affect hepatic lipid content and adipose tissue oxidative stress markers in obese and type 2 diabetic mice

Growing evidence suggests that the consumption of dairy products may contribute to a reduced incidence of cardiovascular risk factors, such as obesity, dyslipidemia, and type 2 diabetes. The fatty acid composition in milk fat, the duration of ripening, and the complexity of the food matrices are important factors that may interfere with the physiological impact. In this study, we treated genetic obese and type 2 diabetic mice (db/db) for 4 weeks with different dairy (cheese-based) products, differing by the duration of ripening (0, 15, or 35 days). We found that 35 days ripened product significantly improved glucose tolerance, an effect associated with a decreased adipose tissue lipid peroxide markers (TBARS and NAPDH-oxidase mRNA expression), without affecting body weight, food intake, and fat mass. Both fermented matrices significantly decreased the hepatic lipid content, without modifying plasma triglycerides or plasma total cholesterol. These data suggest that dairy products issued from longer ripening positively impact glucose tolerance, hepatic steatosis, and adipose tissue oxidative stress. Further investigations are warranted to decipher the interactions between milk products fermentation, lipids, and host metabolism