Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

The Framing of Sustainable Consumption and Production in SDG

This paper examines the processes of formulation of UN Sustainable Development Goal 12 (SDG 12) – ‘Ensure Sustainable Consumption and Production Patterns’ – and its targets and indicators. We argue that business interests have steered its narrative of sustainable growth. The outcome of the SDG 12 negotiations reflects a production- and design-centered perspective that emerged in the 1990s and has a business-friendly regulatory approach and faith in solutions through new technologies. We show how the targets and indicators emerged in debates between national governments, UN agencies, civil society and private sector organizations – and how they reflect both the political process and technical and practical considerations in translation of a broad concept into the SDG format. While the emergence of SDG 12 as a standalone goal stems from a push by developing countries to build pressure on developed countries, and its presence may open space for attention to this area in the future, many of its targets were watered down and left vague. The indicators to measure progress on the targets further narrow the scope and ambition of Goal 12, whose current content does not adequately reflect earlier more transformative conceptualizations of Sustainable Consumption and Production

Levels of digestible isoleucine on performance, carcass traits and organs weight of gilts (15 - 30 KG) Níveis de isoleucina digestível sobre o desempenho, características de carcaça e peso de órgãos de fêmeas suínas (15 - 30 kg)

The ideal protein concept for pigs has allowed reducing levels of crude protein in the diet, since synthetic amino acids are included because the branched chain amino acids may be limiting. In order to determine the digestible isoleucine requirement for gilts from 15 to 30 kg, a performance assay was accomplished, using 40 crossbreed gilts of high genetic potential, averaging 15.00 ± 0.52 kg of body weight, alloted in a randomized blocks design, consisting of five treatments (0.45, 0.52, 0.59, 0.66, 0.73% of digestible isoleucine), four replicates and two animals per experimental unit. Performance traits were determined and at the end of the experiment one animal per experimental unit was slaughtered to determine carcass composition and organs weight. Levels from 0.45 to 0.73% of digestible isoleucine did not affect the carcass traits and organs weight of gilts from 15 to 30 kg. A quadratic effect (P<0.05) of digestible isoleucine levels on isoleucine efficiency for weight gain was observed, that increased up to 0.506% digestible isoleucine, which ratio of digestible isoleucine: lysine was 0.51.<br>O conceito de proteína ideal, para suínos, tem permitido reduzir os níveis de proteína bruta da dieta, desde que haja a inclusão de aminoácidos sintéticos, pois os aminoácidos de cadeia ramificada podem ser limitantes. Com o objetivo de determinar a exigência de isoleucina digestível para fêmeas suínas dos 15 aos 30 kg, foi realizado um ensaio de desempenho, utilizando-se 40 fêmeas suínas, mestiças de alto potencial genético, com peso vivo inicial de 15,00 ± 0,52kg, distribuídas em um delineamento experimental de blocos ao acaso, constituído de cinco tratamentos (0,45; 0,52; 0,59; 0,66; 0,73% de isoleucina digestível), quatro repetições e dois animais por unidade experimental. Foram determinadas características de desempenho e, ao final do experimento, um animal de cada unidade experimental foi abatido, para a determinação da composição de carcaça e peso de órgãos. Níveis de 0,45 a 0,73% de isoleucina digestível não influenciaram as características de carcaça e peso de órgãos dos animais. Houve efeito quadrático (P<0,05) dos níveis de isoleucina digestível sobre a eficiência de utilização de isoleucina para ganho de peso, com aumento até o nível 0,506%; cuja relação isoleucina:lisina digestível foi de 0,51