Centrality dependence of 2-particle correlations in relativistic heavy ion collisions

Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Physics, 2009.Includes bibliographical references (p. 63-64).Results on the centrality dependence of two-particle correlations in Au+Au collisions at ... 200GeV are presented. A particular focus is devoted to investigating any anomalous behavior in the centrality dependence of correlation functions, as previous results suggest existence of such tendencies around Npart [approx.] 50. Correlation functions are calculated for a wide kinematic region of ... from data obtained by the PHOBOS experiment at RHIC. The RHIC layout and the PHOBOS detector setup is discussed. Data acquisition method employed by the PHOBOS experiment, data processing procedures and event selection criteria are presented. The two-particle correlation function is defined and calculation procedures are described. Decomposition analysis is explained as the fit function and the constituting components are introduced. Analysis results for correlation functions and fits are presented. The results suggest that in the kinematic region covered by the analysis of this thesis, no anomalous trends in component behavior exists.by Youngsoo Park.S.B

Concordance Cosmology?

We propose a new intuitive metric for evaluating the tension between two experiments, and apply it to several data sets. While our metric is non-optimal, if evidence of tension is detected, this evidence is robust and easy to interpret. Assuming a flat $\Lambda$CDM cosmological model, we find that there is a modest $2.2\sigma$ tension between the DES Year 1 results and the ${\it Planck}$ measurements of the Cosmic Microwave Background (CMB). This tension is driven by the difference between the amount of structure observed in the late-time Universe and that predicted from fitting the ${\it Planck}$ data, and appears to be unrelated to the tension between ${\it Planck}$ and local esitmates of the Hubble rate. In particular, combining DES, Baryon Acoustic Oscillations (BAO), Big-Bang Nucleosynthesis (BBN), and supernovae (SNe) measurements recovers a Hubble constant and sound horizon consistent with ${\it Planck}$, and in tension with local distance-ladder measurements. If the tension between these various data sets persists, it is likely that reconciling ${\it all}$ current data will require breaking the flat $\Lambda$CDM model in at least two different ways: one involving new physics in the early Universe, and one involving new late-time Universe physics.Comment: 8 pages. 5 figure

荷電粒子ビームを模擬した純電子プラズマの緩和過程に関する実験研究

13301甲第4926号博士（理学）金沢大学博士論文本文Ful

Effects of Temperature on Development and Voltinism of Chaetodactylus krombeini (Acari: Chaetodactylidae): Implications for Climate Change Impacts

Temperature plays an important role in the growth and development of arthropods, and thus the current trend of climate change will alter their biology and species distribution. We used Chaetodactylus krombeini (Acari: Chaetodactylidae), a cleptoparasitic mite associated with Osmia bees (Hymenoptera: Megachilidae), as a model organism to investigate how temperature affects the development and voltinism of C. krombeini in the eastern United States. The effects of temperature on the stage-specific development of C. krombeini were determined at seven constant temperatures (16.1, 20.2, 24.1, 27.5, 30.0, 32.4 and 37.8°C). Parameters for stage-specific development, such as threshold temperatures and thermal constant, were determined by using empirical models. Results of this study showed that C. krombeini eggs developed successfully to adult at all temperatures tested except 37.8°C. The nonlinear and linear empirical models were applied to describe quantitatively the relationship between temperature and development of each C. krombeini stage. The nonlinear Lactin model estimated optimal temperatures as 31.4, 32.9, 32.6 and 32.5°C for egg, larva, nymph, and egg to adult, respectively. In the linear model, the lower threshold temperatures were estimated to be 9.9, 14.7, 13.0 and 12.4°C for egg, larva, nymph, and egg to adult, respectively. The thermal constant for each stage completion were 61.5, 28.1, 64.8 and 171.1 degree days for egg, larva, nymph, and egg to adult, respectively. Under the future climate scenarios, the number of generations (i.e., voltinism) would increase more likely by 1.5 to 2.0 times by the year of 2100 according to simulation. The findings herein firstly provided comprehensive data on thermal development of C. krombeini and implications for the management of C. krombeini populations under global warming were discussed

Identification and purification of a soluble region of BubR1: a critical component of the mitotic checkpoint complex

The mitotic checkpoint complex (MCC) ensures the fidelity of chromosomal segregation, by delaying the onset of anaphase until all sister chromatids have been properly attached to the mitotic spindle. In essence, this MCC-induced delay is achieved via the inhibition of the anaphase-promoting complex (APC). Among the components of the MCC, BubR1 plays two major roles in the functions of the mitotic checkpoint. First, BubR1 is able to inhibit APC activity, either by itself or as a component of the MCC, by sequestering a APC coactivator, known as Cdc20. Second, BubR1 activates mitotic checkpoint signaling cascades by binding to the centromere-associated protein E, a microtubule motor protein. Obtaining highly soluble BubR1 is a prerequisite for the study of its structure. BubR1 is a multi-domain protein, which includes a KEN box motif, a mad3-like region, a Bub3 binding domain, and a kinase domain. We obtained a soluble BubR1 construct using a three-step expression strategy. First, we obtained two constructs from BLAST sequence homology searches, both of which were expressed abundantly in the inclusion bodies. We then adjusted the lengths of the two constructs by secondary structure prediction, thereby generating partially soluble constructs. Third, we optimized the solubility of the two constructs by either chopping or adding a few residues at the C-terminus. Finally, we obtained a highly soluble BubR1 construct via the Escherichia coli expression system, which allowed for a yield of 10.8 mg/L culture. This report may provide insight into the design of highly soluble constructs of insoluble multi-domain proteins