Making top-heavy IMFs from canonical IMFs near the galactic centre

We show that dynamical evolution in a strong (Galactic Centre-like) tidal field can create clusters that would appear to have very top-heavy IMFs. The tidal disruption of single star forming events can leave several bound ‘clusters’ spread along 20 pc of the orbit within 1-2 Myr. These surviving (sub)clusters tend to contain an over-abundance of massive stars, with low-mass stars tending to be spread along the whole ‘tidal arm’. Therefore observing a cluster in a strong tidal field with a top-heavy IMF might well not mean the stars formed with a top-heavy IMF

Asymptotic Symmetry and the General Black Hole Solution in Ads_3 Gravity

We describe the Brown-Henneaux asymptotic symmetry of the general black holes in the Chern-Simons gauge theory of the gauge group $SL(2;{\bf R})_L\times SL(2;{\bf R})_R$. We make it clear that the vector-like subgroup $SL(2; {\bf R})_{L+R}$ plays an essential role in describing the asymptotic symmetry consistently. We find a quite general black hole solution in the $AdS_3$ gravity theory. The solution is specified by an infinite number of conserved quantities which constitute a family of mapping from $S^1$ to the gauge group. The BTZ black hole is one of the simplest case.Comment: 19 pages, no figur

Log canonical thresholds of Del Pezzo Surfaces in characteristic p

The global log canonical threshold of each non-singular complex del Pezzo surface was computed by Cheltsov. The proof used Koll\'ar-Shokurov's connectedness principle and other results relying on vanishing theorems of Kodaira type, not known to be true in finite characteristic. We compute the global log canonical threshold of non-singular del Pezzo surfaces over an algebraically closed field. We give algebraic proofs of results previously known only in characteristic $0$. Instead of using of the connectedness principle we introduce a new technique based on a classification of curves of low degree. As an application we conclude that non-singular del Pezzo surfaces in finite characteristic of degree lower or equal than $4$ are K-semistable.Comment: 21 pages. Thorough rewrite following referee's suggestions. To be published in Manuscripta Mathematic

Pharmaceutical Properties of Nanoparticulate Formulation Composed of TPGS and PLGA for Controlled Delivery of Anticancer Drug

A suitable management of the pharmaceutical property is needed and helpful to design a desired nanoparticulate delivery system, which includes the carrier nature, particle size and size distribution, morphology, surfactant stabiliser according to the technique applied, drug-loading ratio and encapsulation efficiency, surface property, etc. All will influence the in vitro release, in vivo behaviour and tissue distribution of administered particulate drug loaded nanoparticles. The main purpose of the present work was to determine the effect of drug loading ratio when employing TPGS as surfactant stabiliser and/or matrix material to improve the nanoparticulate formulation. The model drug employed was paclitaxel.Singapore-MIT Alliance (SMA

Evolution of asexual and sexual reproduction in the aspergilli

Aspergillus nidulans has long-been used as a model organism to gain insights into the genetic basis of asexual and sexual developmental processes both in other members of the genus Aspergillus, and filamentous fungi in general. Paradigms have been established concerning the regulatory mechanisms of conidial development. However, recent studies have shown considerable genome divergence in the fungal kingdom, questioning the general applicability of findings from Aspergillus, and certain longstanding evolutionary theories have been questioned. The phylogenetic distribution of key regulatory elements of asexual reproduction in A. nidulans was investigated in a broad taxonomic range of fungi. This revealed that some proteins were well conserved in the Pezizomycotina (e.g. AbaA, FlbA, FluG, NsdD, MedA, and some velvet proteins), suggesting similar developmental roles. However, other elements (e.g. BrlA) had a more restricted distribution solely in the Eurotiomycetes, and it appears that the genetic control of sporulation seems to be more complex in the aspergilli than in some other taxonomic groups of the Pezizomycotina. The evolution of the velvet protein family is discussed based on the history of expansion and contraction events in the early divergent fungi. Heterologous expression of the A. nidulans abaA gene in Monascus ruber failed to induce development of complete conidiophores as seen in the aspergilli, but did result in increased conidial production. The absence of many components of the asexual developmental pathway from members of the Saccharomycotina supports the hypothesis that differences in the complexity of their spore formation is due in part to the increased diversity of the sporulation machinery evident in the Pezizomycotina. Investigations were also made into the evolution of sex and sexuality in the aspergilli. MAT loci were identified from the heterothallic Aspergillus (Emericella) heterothallicus and Aspergillus (Neosartorya) fennelliae and the homothallic Aspergillus pseudoglaucus (=Eurotium repens). A consistent architecture of the MAT locus was seen in these and other heterothallic aspergilli whereas much variation was seen in the arrangement of MAT loci in homothallic aspergilli. This suggested that it is most likely that the common ancestor of the aspergilli exhibited a heterothallic breeding system. Finally, the supposed prevalence of asexuality in the aspergilli was examined. Investigations were made using A. clavatus as a representative ‘asexual’ species. It was possible to induce a sexual cycle in A. clavatus given the correct MAT1-1 and MAT1-2 partners and environmental conditions, with recombination confirmed utilising molecular markers. This indicated that sexual reproduction might be possible in many supposedly asexual aspergilli and beyond, providing general insights into the nature of asexuality in fungi.National Natural Science Foundation of China 31601446National Research Foundation of Korea 2016010945Intelligent Synthetic Biology Center of Global Frontier Projects 2015M3A6A8065838Biotechnology and Biological Sciences Research CouncilGovernment of IraqMinisterio de Economía y Competitividad BIO2015-67148-

Time and Amplitude of Afterpulse Measured with a Large Size Photomultiplier Tube

We have studied the afterpulse of a hemispherical photomultiplier tube for an upcoming reactor neutrino experiment. The timing, the amplitude, and the rate of the afterpulse for a 10 inch photomultiplier tube were measured with a 400 MHz FADC up to 16 \ms time window after the initial signal generated by an LED light pulse. The time and amplitude correlation of the afterpulse shows several distinctive groups. We describe the dependencies of the afterpulse on the applied high voltage and the amplitude of the main light pulse. The present data could shed light upon the general mechanism of the afterpulse.Comment: 11 figure

Thermodynamics and evaporation of the noncommutative black hole

We investigate the thermodynamics of the noncommutative black hole whose static picture is similar to that of the nonsingular black hole known as the de Sitter-Schwarzschild black hole. It turns out that the final remnant of extremal black hole is a thermodynamically stable object. We describe the evaporation process of this black hole by using the noncommutativity-corrected Vaidya metric. It is found that there exists a close relationship between thermodynamic approach and evaporation process.Comment: 16 pages, 6 figures, added references, to appear in JHE

Single-filament Composite MgB2/SUS Ribbons by Powder-In-Tube Process

We report the successful fabrication of single-filament composite MgB2/SUS ribbons, as an ultra-robust conductor type, employing the powder-in-tube (PIT) process, by swaging and cold rolling only. The remarkable transport critical current (Ic) of the non-sintered MgB2/SUS ribbon has observed, as an unexpected result. Transport critical currents Ic ~ 316 A at T = 4.2 K and Ic ~ 82 A at T = 20 K were observed at self-field, for the non-sintered composite MgB2/SUS ribbon. In addition, the persistent current density Jp values, that were estimated by Bean formula, were more than ~ 7  105 A/cm2 at T = 5 K, and ~ 1.2  105 A/cm2 at T = 30 K, for the sintered composite MgB2/SUS ribbon, at H = 0 G.Comment: 10 pages, 4 figure

On the Thermodynamic Geometry of BTZ Black Holes

We investigate the Ruppeiner geometry of the thermodynamic state space of a general class of BTZ black holes. It is shown that the thermodynamic geometry is flat for both the rotating BTZ and the BTZ Chern Simons black holes in the canonical ensemble. We further investigate the inclusion of thermal fluctuations to the canonical entropy of the BTZ Chern Simons black holes and show that the leading logartithmic correction due to Carlip is reproduced. We establish that the inclusion of thermal fluctuations induces a non zero scalar curvature to the thermodynamic geometry.Comment: 1+17 pages, LaTeX, 4 eps figure

Partially spin polarized quantum Hall effect in the filling factor range 1/3 < nu < 2/5

The residual interaction between composite fermions (CFs) can express itself through higher order fractional Hall effect. With the help of diagonalization in a truncated composite fermion basis of low-energy many-body states, we predict that quantum Hall effect with partial spin polarization is possible at several fractions between $\nu=1/3$ and $\nu=2/5$. The estimated excitation gaps are approximately two orders of magnitude smaller than the gap at $\nu=1/3$, confirming that the inter-CF interaction is extremely weak in higher CF levels.Comment: 4 pages, 3 figure