4 research outputs found
Histopathological reaction in the vestibule after cochlear implantation in Macaca fascicularis.
Cochlear implantation surgery (CI) is considered a safe procedure and is the standard treatment for the auditory
rehabilitation in patients with severe-to-profound sensorineural hearing loss. Although the development of
minimally traumatic surgical concepts (MTSC) have enabled the preservation of residual hearing after the implantation, there is scarce literature regarding the vestibular affection following MTCS.
The aim of the study is to analyze histopathologic changes in the vestibule after CI in an animal model (Macaca
fascicularis). Cochlear implantation was performed successfully in 14 ears following MTCS. They were classified
in two groups upon type of electrode array used. Group A (n = 6) with a FLEX 28 electrode array and Group B (n
= 8) with HL14 array. A 6-month follow-up was carried out with periodic objective auditory testing. After their
sacrifice, histological processing and subsequent analysis was carried out. Intracochlear findings, vestibular
presence of fibrosis, obliteration or collapse is analyzed. Saccule and utricle dimensions and neuroepithelium
width is measured.
Cochlear implantation was performed successfully in all 14 ears through a round window approach. Mean
angle of insertion was >270◦ for group A and 180–270◦ for group B. In group A auditory deterioration was
observed in Mf 1A, Mf2A and Mf5A with histopathological signs of scala tympani ossification, saccule collapse
(Mf1A and Mf2A) and cochlear aqueduct obliteration (Mf5A). Besides, signs of endolymphatic sinus dilatation
was seen for Mf2B and Mf5A. Regarding group B, no auditory deterioration was observed. Histopathological
signs of endolymphatic sinus dilatation were seen in Mf 2B and Mf 8B.
In conclusion, the risk of histological damage of the vestibular organs following minimally traumatic surgical
concepts and the soft surgery principles is very low. CI surgery is a safe procedure and it can be done preserving
the vestibular structures
COVID-19 infection and its influence in otorhinolaryngology-head and neck surgery
Introduction The novel coronavirus disease 2019 pandemic has rapidly spread
worldwide, challenging healthcare resources and communities to an
unprecedent degree. Simultaneously, the amount of clinical and scientific information
released has overwhelmed journal platforms.
Objectives This review aims to summarize the available diagnostic tools and current
guidelines to safely assist patients while limiting the exposure of otolaryngologists
during this pandemic.
Data Synthesis Key articles were retrieved from the following databases: PubMed,
Lancet, Springer Nature, BioMed Central, JAMA network and MEDLINE, as well as updated
documents from the Spanish Ministry of Health, World Health Organization, Centers for
Disease Control and Prevention, Spanish Association of Surgeons, ENT-UK, American
College of Surgeons, and American Academy of Otolaryngology-Head and Neck Surgery.
The terms used for the search were: COVID-19, Test COVID, Surgery in COVID, 2019-nCoV,
‘coronavirus’, and SARS-CoV-2. A total of 10,245 papers were retrieved. The inclusion criteria
for the review included: COVID-19 testing (n ¼ 531), society guidelines for otolaryngologyhead and neck surgery patient care in the outpatient clinic (n ¼ 10) and surgical (n ¼ 18)
settings. Studies not related to COVID-19 diagnosis were excluded.
Conclusion Healthcare institutions around the world are outlining their own protocols
regarding laboratory testing and personnel protective equipment usage based upon
medical societies recommendations during the COVID-19 pandemic. We have summarized
the available laboratory tests and their respective sensitivity and specificity. Moreover,
clinical guidelines from different societies were reviewed and summarized to facilitate
guidance for otolaryngologists in the operating room and in the clinical settings
Histopathological reaction in the vestibule after cochlear implantation in Macaca fascicularis.
Cochlear implantation surgery (CI) is considered a safe procedure and is the standard treatment for the auditory
rehabilitation in patients with severe-to-profound sensorineural hearing loss. Although the development of
minimally traumatic surgical concepts (MTSC) have enabled the preservation of residual hearing after the implantation, there is scarce literature regarding the vestibular affection following MTCS.
The aim of the study is to analyze histopathologic changes in the vestibule after CI in an animal model (Macaca
fascicularis). Cochlear implantation was performed successfully in 14 ears following MTCS. They were classified
in two groups upon type of electrode array used. Group A (n = 6) with a FLEX 28 electrode array and Group B (n
= 8) with HL14 array. A 6-month follow-up was carried out with periodic objective auditory testing. After their
sacrifice, histological processing and subsequent analysis was carried out. Intracochlear findings, vestibular
presence of fibrosis, obliteration or collapse is analyzed. Saccule and utricle dimensions and neuroepithelium
width is measured.
Cochlear implantation was performed successfully in all 14 ears through a round window approach. Mean
angle of insertion was >270◦ for group A and 180–270◦ for group B. In group A auditory deterioration was
observed in Mf 1A, Mf2A and Mf5A with histopathological signs of scala tympani ossification, saccule collapse
(Mf1A and Mf2A) and cochlear aqueduct obliteration (Mf5A). Besides, signs of endolymphatic sinus dilatation
was seen for Mf2B and Mf5A. Regarding group B, no auditory deterioration was observed. Histopathological
signs of endolymphatic sinus dilatation were seen in Mf 2B and Mf 8B.
In conclusion, the risk of histological damage of the vestibular organs following minimally traumatic surgical
concepts and the soft surgery principles is very low. CI surgery is a safe procedure and it can be done preserving
the vestibular structures
COVID-19 infection and its influence in otorhinolaryngology-head and neck surgery
Introduction The novel coronavirus disease 2019 pandemic has rapidly spread
worldwide, challenging healthcare resources and communities to an
unprecedent degree. Simultaneously, the amount of clinical and scientific information
released has overwhelmed journal platforms.
Objectives This review aims to summarize the available diagnostic tools and current
guidelines to safely assist patients while limiting the exposure of otolaryngologists
during this pandemic.
Data Synthesis Key articles were retrieved from the following databases: PubMed,
Lancet, Springer Nature, BioMed Central, JAMA network and MEDLINE, as well as updated
documents from the Spanish Ministry of Health, World Health Organization, Centers for
Disease Control and Prevention, Spanish Association of Surgeons, ENT-UK, American
College of Surgeons, and American Academy of Otolaryngology-Head and Neck Surgery.
The terms used for the search were: COVID-19, Test COVID, Surgery in COVID, 2019-nCoV,
‘coronavirus’, and SARS-CoV-2. A total of 10,245 papers were retrieved. The inclusion criteria
for the review included: COVID-19 testing (n ¼ 531), society guidelines for otolaryngologyhead and neck surgery patient care in the outpatient clinic (n ¼ 10) and surgical (n ¼ 18)
settings. Studies not related to COVID-19 diagnosis were excluded.
Conclusion Healthcare institutions around the world are outlining their own protocols
regarding laboratory testing and personnel protective equipment usage based upon
medical societies recommendations during the COVID-19 pandemic. We have summarized
the available laboratory tests and their respective sensitivity and specificity. Moreover,
clinical guidelines from different societies were reviewed and summarized to facilitate
guidance for otolaryngologists in the operating room and in the clinical settings