A prospective randomised clinical trial of prophylactic antibiotic in caesarean delivery and fetomaternal outcome

Background: Infectious maternal and perinatal morbidities are 5 to 20 times more in caesarean section when compared to vaginal births. Objective of present study was to assess the rates of maternal and neonatal infectious morbidities following administration of antibiotic before skin incision compared to given after umbilical cord clamping during caesarean delivery.Methods: 185 pregnant women with gestational periods more than 34 weeks who were prepared for caesarean delivery, randomized to single dose antibiotic given either before skin incision (study group) or after umbilical cord clamping (control group). Primary outcome measures: maternal postoperative infections morbidities. Secondary outcome measures: neonatal infections morbidities with Sick Newborn Care Unit (SNCU) admissions and postoperative hospital stay of mother.Results: Surgical Site Infections (SSI) and postoperative fever were significantly less in the study group than the control group so also the lesser incidences of endometritis but no statistically significant difference in the incidence of peritonitis and wound dehiscence were observed in both groups. No significant differences were seen in neonatal infectious morbidities and SNCU admission when compared in both groups. There was significantly less mean postoperative hospital stay of mothers in the group who received prophylactic antibiotic pre-incision.Conclusions: Antibiotic given 30-60 minutes before skin incision significantly decreases maternal postoperative infectious morbidities barring neonate

Evaluation of morphine, methadone, digoxin, and dronabinol poisoning during the years 2017 to 2019 in Ilam, Iran

Background: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam. Methods: In this In this Cross-sectional study, patient samples suspected of morphine, methadone, digoxin, and dronabinol poisoning referred to the toxicology laboratory of Ilam University of Medical Sciences were analyzed using the HPLC method, and the results were analysed using SPSS software. Results: Results showed that the percentage of drug use is greater in men than in women. The highest percentage of morphine and methadone poisonings were detected in those under the age of 40, whereas the highest percentage of digoxin poisonings were recorded in those over the age of 80. As a result, the average age of digoxin users was substantially greater in men than in women. Methadone consumers showed significantly greater blood levels than others. In addition, there was a significant difference (P<0.01) in blood levels between men and women who used morphine. Conclusion: In general, it is important to understand the status of drug poisoning with drugs such as morphine, methadone, digoxin, and dronabinol, as well as the prognosis associated with the treatment process of such poisoning. &#160

An insight of environmental contamination of arsenic on animal health

The main threats to human health from heavy metals are associated with exposure to lead, cadmium, mercury and arsenic. Exposure to arsenic is mainly via intake of food and drinking water, food being the most important source in most populations. Although adverse health effects of heavy metals have been known for a long time, exposure to heavy metals continues and is even increasing in some areas. Long-term exposure to arsenic in drinking-water is mainly related to increased risks of skin cancer, but also some other cancers, as well as other skin lesions such as hyperkeratosis and pigmentation changes. Therefore, measures should be taken to reduce arsenic exposure in the general population in order to minimize the risk of adverse health effects. Animal are being exposed to arsenic through contaminated drinking water, feedstuff, grasses, vegetables and different leaves. Arsenic has been the most common causes of inorganic chemical poisoning in farm animals. Although, sub-chronic and chronic exposure of arsenic do not generally reveal external signs or symptoms in farm animals but arsenic (or metabolites) concentrations in blood, hair, hoofs and urine are remained high in animals of arsenic contaminated zones. So it is assumed that concentration of arsenic in blood, urine, hair or milk have been used as biomarkers of arsenic exposure in field animals

WATER WAVES GENERATED BY DISTURBANCES AT

This paper is concerned with two-dimensional unsteady motion of water waves generated by an initial disturbance created at an ice sheet covering the water. The ice cover is modeled as a thin elastic plate. Using linear theory, the problem is formulated as an initial value problem for the velocity potential describing the motion in the liquid. In the mathematical analysis, the Laplace and Fourier transform techniques have been utilized to obtain the depression of the ice-covered surface in the form of an infinite integral. For the special case of initial disturbance concentrated at the origin, taken on the ice cover, this integral is evaluated asymptotically by the method of a stationary phase for a long time and large distance from the origin. The form of the ice-covered surface is graphically depicted for two types of initial disturbances. 1

Impact and Biomechanical Mechanisms of Tortuosity of Abdominal aorta- A Case Report

Abdominal aorta is the major arterial avenue to supply oxygenated blood to human body.Its luminal diam-eter,thickness and tortuosity are predisposing factors for variation of blood pressure. We report a case where there is buckling of the abdominal aorta in an elderly female.In the present cadaveric study we have analysed the possible factors that might produce such deformity. The knowledge of anatomic characteris-tics of abdominal aorta , and early detection by clinical symptoms and radiological diagnosis can prevent catastrophe. [Natl J Med Res 2016; 6(2.000): 219-221

A prospective randomised clinical trial of prophylactic antibiotic in caesarean delivery and fetomaternal outcome

Background: Infectious maternal and perinatal morbidities are 5 to 20 times more in caesarean section when compared to vaginal births. Objective of present study was to assess the rates of maternal and neonatal infectious morbidities following administration of antibiotic before skin incision compared to given after umbilical cord clamping during caesarean delivery.Methods: 185 pregnant women with gestational periods more than 34 weeks who were prepared for caesarean delivery, randomized to single dose antibiotic given either before skin incision (study group) or after umbilical cord clamping (control group). Primary outcome measures: maternal postoperative infections morbidities. Secondary outcome measures: neonatal infections morbidities with Sick Newborn Care Unit (SNCU) admissions and postoperative hospital stay of mother.Results: Surgical Site Infections (SSI) and postoperative fever were significantly less in the study group than the control group so also the lesser incidences of endometritis but no statistically significant difference in the incidence of peritonitis and wound dehiscence were observed in both groups. No significant differences were seen in neonatal infectious morbidities and SNCU admission when compared in both groups. There was significantly less mean postoperative hospital stay of mothers in the group who received prophylactic antibiotic pre-incision.Conclusions: Antibiotic given 30-60 minutes before skin incision significantly decreases maternal postoperative infectious morbidities barring neonate

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Not AvailableImpact of osmoregulation on plasma sex steroid levels and gonadal histo-architecture was monitored to elucidate the effects of deviation from habitat salinity on gonadal recrudescence in an active reproductive season of an euryhaline fish Etroplus suratensis (pearlspot). Fish were maintained in three different salinities of 0 ppt Fresh Water (FW), 15 ppt Brackish Water (BW) and 30 ppt Sea Water (SW) for a period of 60 days. Plasma osmolality values were found to be significantly highest in SW-acclimated fish accompanied by highest levels of plasma K⁺ and Cl¯ ions. The progress of gonadal recrudescence was higher in BW followed by FW and SW as evident from the cellular features of gonads and increased level of plasma sex steroids, such as, in case of female and 11-keto Testosterone and Testosterone in case of males. Plasma cortisol levels were comparatively higher in fish of both sexes in SW group. Significantly high levels of cortisol in SW suggest its role in hypo-osmoregulation and associated stress. This study clearly reveals that salinity changes during the active reproductive phase can suppress the steroid-mediated gonad recrudescence maximally under hypo-osmoregulation in an euryhaline fish.Not Availabl