13 research outputs found

    Performance of the Determine Ag/Ab Combo test.

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    <p>Group 1: Antigen positive, antibody negative acute HIV infection (Ag+Abāˆ’).</p><p>Group 2: Antigen positive, antibody positive early HIV infection (Ag+Ab+).</p><p>Group 3: Antigen negative, antibody positive chronic HIV infection (Agāˆ’Ab+).</p><p>Group 4: Antigen negative, antibody negative volunteers without HIV infection (Agāˆ’Abāˆ’).</p><p>Group 5: Antigen false positive, antibody negative volunteers without HIV infection (Agāˆ’Abāˆ’).</p><p>Ag: p24 antigen, Ab: HIV antibody, weak pos: the respective assay indicator was fainter than the control indicator. This is considered ā€œpositiveā€ in our analyses, as per the package insert.</p

    ELISA p24 Antigen Concentration and Viral Load Summary Statistics.

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    *<p>Upper limit of detection for the VL assay ā€Š=ā€Š15,000,000, any observation that exceeded 15,000,000 recorded as 15,000,001.</p><p>Group 1: Antigen positive, antibody negative i.e. acute HIV infection (Ag+ Abāˆ’).</p><p>Group 2: Antigen positive, antibody positive i.e. early HIV infection (Ag+ Ab+).</p

    HIV incidence and sex at each study site.

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    <p>*Cases per 100 person-years (95% CI). Stratified by sex only when the difference was statistically significant (p<0.05)</p><p>For more details, see [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134438#pone.0134438.ref015" target="_blank">15</a>]</p><p>HIV incidence and sex at each study site.</p

    Demographic characteristics of the suspected transmitting partners of incident cases reported to be in HIV discordant couple relationships.

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    <p>* Data or sample not available from one or both volunteers</p><p>** Transmitting partner reports use of antiretroviral therapy, EDI: Estimated date of infection in the incident case</p><p>Ā°An additional 6 volunteers reported being on ART at or around the time of the transmission event, however their viral load was too low to sequence for linkage analysis</p><p><sup>ā–Ŗ</sup> Comparing linked vs. unlinked across volunteer characteristic</p><p><sup>ā–Ŗā–Ŗ</sup> Divorced, separated or widowed</p><p>Demographic characteristics of the suspected transmitting partners of incident cases reported to be in HIV discordant couple relationships.</p

    HIV prevalence and multivariate predictors of prevalent HIV infection in Masaka, Kilifi and Nairobi.

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    <p>PR: Prevalence Ratio, CI: Confidence Interval, ref: reference group, NA: data were not collected at this CRC, NS: data were not significant predictors of prevalent HIV in multivariate modeling</p><p><sup>*</sup> In Masaka condom use was measured with the question: Have you and your partner ever used a condom (yes/no), and if so, how often do you use a condom (Always, more than half of the time, about half of the time, rarely or less than half of the time)? In Kilifi: In the past 12 months, have you used a condom never, sometimes or always during sex? In Kangemi: Have you used a condom before (yes/no)?</p><p><sup>**</sup> Due to collinearity in the covariates, model failed to converge with discharge and ulcers considered together</p><p><sup>***</sup> In Kangemi, all volunteers were sexually active, but not all volunteers were sexually active in the past 7 days</p><p>HIV prevalence and multivariate predictors of prevalent HIV infection in Masaka, Kilifi and Nairobi.</p
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