1 research outputs found
Photocatalysis by 3,6-Disubstituted‑<i>s</i>‑Tetrazine: Visible-Light Driven Metal-Free Green Synthesis of 2‑Substituted Benzimidazole and Benzothiazole
<i>s</i>-Tetrazine based molecules were prepared for
visible-light-driven organic transformations. The 3,6-diÂ(pyridin-2-yl)-1,2,4,5-tetrazine
(<b>pytz</b>) derivative shows visible light absorption and
reversible one-electron reduction behavior. In the presence of <b>pytz</b> and aerial oxygen, aldehyde reacts with <i>o</i>-phenylenediamine or <i>o</i>-aminothiophenol under visible
light irradiation at ambient temperature to produce corresponding
2-substituted benzimidazoles and benzothiazoles, respectively. <b>Pytz</b> catalyst demonstrates excellent catalytic activity for
alkyl, aryl, organo-metallic substituted aldehydes and reducing sugar.
The reaction yield is high for both the electron-donating and electron
withdrawing substituents in aromatic aldehydes. The use of a metal-free
catalyst and visible light energy, along with the mild reaction conditions,
makes this reaction an environmentally benign and energy-saving chemical
process