507 research outputs found

    An innovative data mining procedure, using clean algorithm and factor analysis, for irregularly sampled temporal environmental data sets

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    Οι περιβαλλοντικές βάσεις δεδομένων συχνά αντιμετωπίζουν τα προβλήματα της άτακτης δειγματοληψίας στον χρόνο και της έλλειψης μετρήσεων για κάποιες περιόδους. Το γεγονός αυτό εμποδίζει τη χρήση των κλασικών μεθόδων ανάλυσης χρονοσειρών, οι οποίες απαιτούν σταθερό χρονικό βήμα ενώ ταυτόχρονα τα χρονικά κενά εισάγουν δυσκολίες στην χρήση των περισσοτέρων μεθόδων πολυδιάστατης σταπστικής ανάλυσης. Η παρούσα εργασία προτείνει ένα πλήρες μεθοδολογικό σχήμα ανάλυσης χρονικών περιβαλλονπκών δεδομένων με δειγματοληπτική ανομοιογένεια, στο οποίο γίνεται χρήση του αλγορίθμου CLEAN και της Παραγοντικής ανάλυσης (Factor Analysis). Ο αλγόριθμος CLEAN έχει την ικανότητα να αναπλάθει τις αρχικές χρονοσειρές της βάσης δεδομένων χρησιμοποιώντας φασματική ανάλυση και να δημιουργεί καινούργιες με σταθερό χρονικό βήμα και έλλειψη κενών. Λαμβάνει χώρα δηλαδή τόσο συμπλήρωση των κενών τ?/ς βάσης, όσο και «εξυγίανση» της δειγματοληψίας της. Η παραγοντική ανάλυση ομαδοποιεί τις μεταβλητές, ανάλογα με τον περιβαλλοντικό μηχανισμό από τον οποίο κάθε μια ελέγχεται και επιπλέον αποκαλύπτει τη χαρακτηριστική χρονική διακύμανση της κάθε ομάδας. Το συγκεκριμένο μεθοδολογικό σχήμα εφαρμόστηκε με πλήρη επιτυχία σε μια βάση υδροχημικών δεδομένων μεγάλης χρονικής περιόδου (1980-94) στον ποταμό ΣτρυμόναEnvironmental data are often irregularly collected in the time domain due to various reasons which affect the field sampling schedule. As a result, data sets with uneven time step and time periods with no measurements are frequently built. Many problems occur in such data sets when processed owing to that neither statistical nor spectral analysis methods can easily be applied to them without any specific pre-treatment. In our study it is demonstrated a unified methodological scheme especially designed to deal with incomplete and unevenly sampled temporal data sets. This method consists of the CLEAN algorithm and the Factor analysis. The proposed methodology is successfully applied to data sets that belong to two sampling sites of the Greek river Strimona

    Sudden Death and Left Ventricular Involvement in Arrhythmogenic Cardiomyopathy

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    BACKGROUND: Arrhythmogenic cardiomyopathy (ACM) is an inherited heart muscle disorder characterized by myocardial fibrofatty replacement and an increased risk of sudden cardiac death (SCD). Originally described as a right ventricular disease, ACM is increasingly recognized as a biventricular entity. We evaluated pathological, genetic, and clinical associations in a large SCD cohort. METHODS: We investigated 5205 consecutive cases of SCD referred to a national cardiac pathology center between 1994 and 2018. Hearts and tissue blocks were examined by expert cardiac pathologists. After comprehensive histological evaluation, 202 cases (4%) were diagnosed with ACM. Of these, 15 (7%) were diagnosed antemortem with dilated cardiomyopathy (n=8) or ACM (n=7). Previous symptoms, medical history, circumstances of death, and participation in competitive sport were recorded. Postmortem genetic testing was undertaken in 24 of 202 (12%). Rare genetic variants were classified according to American College of Medical Genetics and Genomics criteria. RESULTS: Of 202 ACM decedents (35.4±13.2 years; 82% male), no previous cardiac symptoms were reported in 157 (78%). Forty-one decedents (41/202; 20%) had been participants in competitive sport. The adjusted odds of dying during physical exertion were higher in men than in women (odds ratio, 4.58; 95% CI, 1.54-13.68; P=0.006) and in competitive athletes in comparison with nonathletes (odds ratio, 16.62; 95% CI, 5.39-51.24; P<0.001). None of the decedents with an antemortem diagnosis of dilated cardiomyopathy fulfilled definite 2010 Task Force criteria. The macroscopic appearance of the heart was normal in 40 of 202 (20%) cases. There was left ventricular histopathologic involvement in 176 of 202 (87%). Isolated right ventricular disease was seen in 13%, isolated left ventricular disease in 17%, and biventricular involvement in 70%. Among whole hearts, the most common areas of fibrofatty infiltration were the left ventricular posterobasal (68%) and anterolateral walls (58%). Postmortem genetic testing yielded pathogenic variants in ACM-related genes in 6 of 24 (25%) decedents. CONCLUSIONS: SCD attributable to ACM affects men predominantly, most commonly occurring during exertion in athletic individuals in the absence of previous reported cardiac symptoms. Left ventricular involvement is observed in the vast majority of SCD cases diagnosed with ACM at autopsy. Current Task Force criteria may fail to diagnose biventricular ACM before death

    Monitoring of a methane-seeping pockmark by cabled benthic observatory (Patras Gulf, Greece)

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    A new seafloor observatory, the gas monitoring module (GMM), has been developed for continuous and long-term measurements of methane and hydrogen sulphide concentrations in seawater, integrated with temperature (T), pressure (P) and conductivity data at the seafloor. GMM was deployed in April 2004 within an active gas-bearing pockmark in the Gulf of Patras (Greece), at a water depth of 42 m. Through a submarine cable linked to an onshore station, it was possible to remotely check, via direct phone connection, GMM functioning and to receive data in nearreal time. Recordings were carried out in two consecutive campaigns over the periods April–July 2004, and September 2004–January 2005, amounting to a combined dataset of ca. 6.5 months. This represents the first long-term monitoring ever done on gas leakage from pockmarks by means of CH4+H2S+T+P sensors. The results show frequent T and P drops associated with gas peaks, more than 60 events in 6.5 months, likely due to intermittent, pulsation-like seepage. Decreases in temperature in the order of 0.1–1°C (up to 1.7°C) below an ambient T of ca. 17°C (annual average) were associated with short-lived pulses (10–60 min) of increased CH4+H2S concentrations. This seepage “pulsation” can either be an active process driven by pressure build-up in the pockmark sediments, or a passive fluid release due to hydrostatic pressure drops induced by bottom currents cascading into the pockmark depression. Redundancy and comparison of data from different sensors were fundamental to interpret subtle proxy signals of temperature and pressure which would not be understood using only one sensor.Published297-302JCR Journalreserve

    Palaeoenvironmental implications of a marine geoarchaeological survey conducted in the SW Argosaronic gulf, Greece

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    AbstractA marine geoarcheological survey was conducted at the southwestern end of the Argosaronic gulf in Greece, an area of archaeological importance. The survey was initiated by the discovery of a Late Bronze Age (LBA) shipwreck off Modi Islet. The survey which employed echo-sounding, sub-bottom profiling, side scan sonar systems and sediment coring extended to the area between Poros Island, Modi Islet and Argolid peninsula, aiming to evaluate the changes of the coastal zone extent in the past. The evolution of the palaeo-shoreline over the last 20ka is proposed based on the interpretation of the acquired bathymetric and seismic records, the estimation of the thickness of the marine sediments and the examination of existing datasets of the relative sea level changes in the area.The produced scenarios suggest that major changes marked the extent of the coastal zone since the Paleolithics. During the Upper Paleolithic period, the coast was larger by at least 11km2 and Poros and Modi islands were connected to the Peloponnesus. The sea level rise during the Mesolithic period formed a well-protected bay between Poros Island and Peloponessus and disconnected the Modi Islet from Poros Island. The coastal zone reached the present configuration around Late Bronze Age. The detection and mapping of scarps on the seismic profiles imply that the sea level rise presented standstills at least from the Last Glacial maximum until the onset of Holocene. However, the submerged coasts could be potential areas of archaeological interest since the examined area is habited continuously from the Paleolithic period.The acoustic data sets produced high resolution geomorphological maps at the wreck site which constitute data base for the monitoring of the site. In addition, the examination of the seafloor texture at the wreck site suggests that the seafloor characteristics were unfavorable for the preservation of the shipwreck
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