Mean (SD) estimated glomerular filtration rate (eGFR) of oldest old with and without vascular diseases/risk factors ¹.

<p>C-G: Cockcroft and Gault equation; MDRD: Modification of Diet in Renal Disease formula; MAYO: MAYO Clinic quadratic equation; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration formula; BIS-1: Berlin Initiative Study 1; CI: Confidence Intervals</p><p>^<b>1</b> Vascular diseases/risk factors: diabetes, hypertension, heart failure, myocardial infarction, and stroke.</p><p>² n = 144 (without vascular diseases/risk factors) and n = 515 (with vascular diseases/risk factors).</p><p>Mean (SD) estimated glomerular filtration rate (eGFR) of oldest old with and without vascular diseases/risk factors <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136039#t003fn002" target="_blank">¹</a>.</p

Distribution of estimated Glomerular Filtration Rate (eGFR) according to Cockcroft and Gault equation (C-G); Modification of Diet in Renal Disease (MDRD) formula; MAYO Clinic quadratic equation (MAYO); Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula; Berlin Initiative Study 1 (BIS-1).

<p>Distribution of estimated Glomerular Filtration Rate (eGFR) according to Cockcroft and Gault equation (C-G); Modification of Diet in Renal Disease (MDRD) formula; MAYO Clinic quadratic equation (MAYO); Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula; Berlin Initiative Study 1 (BIS-1).</p

Age groups and sex adjusted survival by estimated Glomerular Filtration Rate (eGFR) according to a) Cockcroft and Gault equation (C-G); b) Modification of Diet in Renal Disease (MDRD) formula; (c) MAYO Clinic quadratic equation (MAYO); d) Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula; e) Berlin Initiative Study 1 (BIS-1).

<p>Age groups and sex adjusted survival by estimated Glomerular Filtration Rate (eGFR) according to a) Cockcroft and Gault equation (C-G); b) Modification of Diet in Renal Disease (MDRD) formula; (c) MAYO Clinic quadratic equation (MAYO); d) Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula; e) Berlin Initiative Study 1 (BIS-1).</p

Baseline Characteristics of the Study Population (N between 622 and 700).

<p>^a BMI, Body Mass Index</p><p>^b Respiratory failure = use of O₂ or bronchodilators</p><p>^cAnemia was defined by the WHO criteria as hemoglobin concentration <12.0 g/mL in women and <13.0 g/mL in men</p><p>^dBUN, Blood Urea Nitrogen.</p><p>Baseline Characteristics of the Study Population (N between 622 and 700).</p

Characteristics of mild anemic (WHO criteria) and non anemic individuals included in the impact study

*<p>Adjusted for oncological status.</p

Flow chart of the study.

<p>Flow chart of the study.</p

Impact of mild grade anemia (WHO criteria) on cognitive, functional, mood, and quality of life variables in elderly individuals (65–84 years)

*<p>Between brackets score ranges with best scores on the right.</p>†<p>Model 1 includes mild anemic and oncological status only; Model 2 includes Model 1 plus age, sex, education, and (except: Geriatric Depression Scale, SF-12 Mental, and FACT scores) Geriatric Depression Scale score; Model 3 includes Model 2 plus hypertension, diabetes, heart failure, myocardial infarction, respiratory failure, neurologic disorders.</p

Impact of mild grade anemia (hemoglobin concentration: women, 10.0–12.1 g/dL; men, 10.0–13.1 g/dL) on cognitive, functional, mood, and quality of life variables in elderly individuals (65–84 years)

*<p>Between brackets score ranges with best scores on the right.</p>†<p>Model 1 includes mild anemic and oncological status only; Model 2 includes Model 1 plus age, sex, education, and (except: Geriatric Depression Scale, SF-12 Mental, and FACT scores) Geriatric Depression Scale score; Model 3 includes Model 2 plus hypertension, diabetes, heart failure, myocardial infarction, respiratory failure, neurologic disorders.</p