Receiver operating characteristic (ROC) curves for the baseline cytokine values comparing LTBI subjects and patients with active TB with non TB patients.

<p>The solid line shows the result of absolute values of each biomarker. The area under the curve (AUC) is indicated.</p

ROC curves features of the 14 markers increased in active TB.

<p>ROC curves features of the 14 markers increased in active TB.</p

Scatter plots showing biomarker concentrations in antigen stimulated supernatants with subtracted Nil value from participants with non TB disease(triangles), LTBI (squares), active TB patients (circle).

<p>Biomarkers were measured by Luminex assay. Median concentrations are indicated with horizontal bars. Statistical differences were analyzed using Kruskall Wallis tests. *p<0.05, ** p<0.01.</p

Receiver operating characteristic (ROC) curves for the cytokines values with subtracted Nil value comparing active TB patients with non TB patients.

<p>The solid line shows the result of the absolute values of each cytokine. The area under the curve (AUC) is indicated.</p

ROC curves features of the 11 markers increased in LTBI.

<p>ROC curves features of the 11 markers increased in LTBI.</p

Medians and statistical analysis of the cytokines baseline levels.

<p>Medians and statistical analysis of the cytokines baseline levels.</p

ROC curves features of markers increased in LTBI and Active TB.

<p>ROC curves features of markers increased in LTBI and Active TB.</p

List of the cytokines, chemokines and growth factors evaluated by luminex assay Biorad (Germany) and their normal range assessed in healthy donors.

<p>List of the cytokines, chemokines and growth factors evaluated by luminex assay Biorad (Germany) and their normal range assessed in healthy donors.</p

Receiver operating characteristic (ROC) curves for the cytokine values with subtracted Nil value comparing LTBI subjects with non TB patients.

<p>The solid line shows the result of the absolute values of each cytokine. The area under the curve (AUC) is indicated.</p

Receiver operating characteristic (ROC) curves for the ML-CD64 index and the Monocyte-CD64 index.

<p>A) The solid line shows the result for the ML-CD64 index value comparing patients with active TB disease to HD. B) The solid line shows the result for the ML-CD64 index value comparing patients with active TB disease to LTBI subjects. C) The solid line shows the result for the monocyte-CD64 index value comparing patients with active TB disease to HD. D) The solid line shows the result for themonocyte-CD64 index value comparing patients with active TB disease to LTBI subjects.</p