Nonequilibrium orbital magnetization of strongly localized electrons

The magnetic response of strongly localized electrons to a time-dependent vector potential is considered. The orbital magnetic moment of the system, away from steady-state conditions, is obtained. The expression involves the tunneling and phonon-assisted hopping currents between localized states. The frequency and temperature dependence of the orbital magnetization is analyzed as function of the admittances connecting localized levels. It is shown that quantum interference of the localized wave functions contributes to the moment a term which follows adiabatically the time-dependent perturbation.Comment: RevTeX 3.

Discrepancy between short-term and long-term effects of bone marrow-derived cell therapy in acute myocardial infarction: a systematic review and meta-analysis

Abstract Background Bone marrow-derived cell therapy has been used to treat acute myocardial infarction. However, the therapeutic efficacy of this approach remains controversial. Here, we performed a systematic review and meta-analysis to evaluate short-term and long-term effectiveness of bone marrow-derived therapy. Methods We searched eight databases (Ovid-Medline, Ovid-EMBASE, Cochrane Library, KoreaMed, KMBASE, KISS, RISS, and KisTi) up to December 2014. Demographic characteristics, clinical outcomes, and adverse events were analyzed. We identified 5534 potentially relevant studies; 405 were subjected to a full-text review. Forty-three studies with 2635 patients were included in this review. Results No safety issues related to cell injection were reported during follow-up. At 6 months, cell-injected patients showed modest improvements in left ventricular ejection fraction (LVEF) compared with the control group. However, there were no differences between groups at other time points. In the cardiac MRI analysis, there were no significant differences in infarct size reduction between groups. Interestingly, mortality tended to be reduced at the 3-year follow-up, and at the 5-year follow-up, cell injection significantly decreased all-cause mortality. Conclusions This meta-analysis demonstrated discrepancies between short-term LV functional improvement and long-term all-cause mortality. Future clinical trials should include long-term follow-up outcomes to validate the therapeutic efficacy of cell therapy

Trajectory Propagation Using Information on Periodicity

Families of methods to integrate first and second order ordinary differential equations whose solution known to be periodic will be discussed. The methods can be tuned to a possibly a-priori knowledge of the user on the location of the frequencies, that are dominant in the exact solution. On the basis of such extra information the truncation error can considerably be reduced in magnitude. The paper compares these methods to well known in integrators and discusses a simple mechanism to estimate the frequency during the integration process