Altered excitation-contraction coupling in human chronic atrial fibrillation

This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening of the atrial action potential duration and effective refractory period, depressed intracellular Ca<sup>2+</sup> transient, and reduced myocyte contractility. Here we summarize the current knowledge of the ionic bases underlying these changes. Understanding the molecular mechanisms of excitation-contraction-coupling remodeling in the fibrillating human atria is important to identify new potential targets for AF therapy

Dynamics of Passive-Scalar Turbulence

We present the first study of the dynamic scaling or multiscaling of passive-scalar and passive-vector turbulence. For the Kraichnan version of passive-scalar and passive-vector turbulence we show analytically, in both Eulerian and quasi-Lagrangian frameworks, that simple dynamic scaling is obtained but with different dynamic exponents. By developing the multifractal model we show that dynamic multiscaling occurs in passive-scalar turbulence only if the advecting velocity field is itself multifractal. We substantiate our results by detailed numerical simulations in shell models of passive-scalar advection.Comment: published versio

Random spread on the family of small-world networks

We present the analytical and numerical results of a random walk on the family of small-world graphs. The average access time shows a crossover from the regular to random behavior with increasing distance from the starting point of the random walk. We introduce an {\em independent step approximation}, which enables us to obtain analytic results for the average access time. We observe a scaling relation for the average access time in the degree of the nodes. The behavior of average access time as a function of $p$, shows striking similarity with that of the {\em characteristic length} of the graph. This observation may have important applications in routing and switching in networks with large number of nodes.Comment: RevTeX4 file with 6 figure

Characterization and control of small-world networks

Recently Watts and Strogatz have given an interesting model of small-world networks. Here we concretise the concept of a ``far away'' connection in a network by defining a {\it far edge}. Our definition is algorithmic and independent of underlying topology of the network. We show that it is possible to control spread of an epidemic by using the knowledge of far edges. We also suggest a model for better advertisement using the far edges. Our findings indicate that the number of far edges can be a good intrinsic parameter to characterize small-world phenomena.Comment: 9 pages and 6 figure

Condensation of Silica Nanoparticles on a Phospholipid Membrane

The structure of the transient layer at the interface between air and the aqueous solution of silica nanoparticles with the size distribution of particles that has been determined from small-angle scattering has been studied by the X-ray reflectometry method. The reconstructed depth profile of the polarizability of the substance indicates the presence of a structure consisting of several layers of nanoparticles with the thickness that is more than twice as large as the thickness of the previously described structure. The adsorption of 1,2-distearoyl-sn-glycero-3-phosphocholine molecules at the hydrosol/air interface is accompanied by the condensation of anion silica nanoparticles at the interface. This phenomenon can be qualitatively explained by the formation of the positive surface potential due to the penetration and accumulation of Na+ cations in the phospholipid membrane.Comment: 7 pages, 5 figure

Direct torque control scheme for a six-phase induction motor with reduced torque ripple

This paper presents an improved direct torque control (DTC) method for an asymmetrical six-phase induction motor using a two-level six-phase inverter. As is well-known, a simple extension of three-phase direct torque control technique to an asymmetrical six-phase motor, using large vectors only, introduces significant current harmonics of the order 6n±1 (n = 1,3,5,…), which are mapped into the non-flux/torque producing (xy) plane. These harmonics cause only losses in the motor winding as they do not take part in torque production. Hence a number of different improved DTC techniques have been developed in the past for multiphase motor drives. The paper takes one such DTC method as the starting point and improves it further by using the concept of virtual voltage vectors. Developed vector selection algorithm, based on two virtual voltage vectors, requires the information on position of the flux in the auxiliary (xy) subspace and provides stator current quality commensurate with the currently available best DTC algorithm for six-phase drives. However, use of two virtual voltage vectors enables a substantial reduction of the torque ripple, which is achieved by means of a five-level torque comparator. Extensive experimentation is performed and it is shown that the reduction of the current harmonics is in essence almost the same as in another recently developed DTC scheme, based on the use of a single virtual voltage vector. However, the achieved torque ripple reduction, which is verified experimentally, makes the scheme superior when compared to the existing approaches. At the same time, developed scheme retains qualities of conventional DTC schemes, such as simple structure and fast response. Its additional beneficial feature is the easiness of implementation

Evidence for Excimer Photoexcitations in an Ordered {\pi}-Conjugated Polymer Film

We report pressure-dependent transient picosecond and continuous-wave photomodulation studies of disordered and ordered films of 2-methoxy-5-(2-ethylhexyloxy) poly(para-phenylenevinylene). Photoinduced absorption (PA) bands in the disordered film exhibit very weak pressure dependence and are assigned to intrachain excitons and polarons. In contrast, the ordered film exhibits two additional transient PA bands in the midinfrared that blueshift dramatically with pressure. Based on high-order configuration interaction calculations we ascribe the PA bands in the ordered film to excimers. Our work brings insight to the exciton binding energy in ordered films versus disordered films and solutions. The reduced exciton binding energy in ordered films is due to new energy states appearing below the continuum band threshold of the single strand.Comment: 5.5 pages, 5 figure

Edge wetting of an Ising three-dimensional system

The effect of edge on wetting and layering transitions of a three-dimensional spin-1/2 Ising model is investigated, in the presence of longitudinal and surface magnetic fields, using mean field (MF) theory and Monte Carlo (MC) simulations. For T=0, the ground state phase diagram shows that there exist only three allowed transitions, namely: surface and bulk transition, surface transition and bulk transition. However, there exist a surface intra-layering temperature $T_{L}^{s}$, above which the surface and the intra-layering surface transitions occur. While the bulk layering and intra-layering transitions appear above an other finite temperature $T_{L}^{b} (\ge T_{L}^{s})$. These surface and bulk intra-layering transitions are not seen in the perfect surfaces case. Numerical values of $T_{L}^{s}$ and $T_{L}^{b}$, computed by Monte Carlo method are found to be smaller than those obtained using mean field theory. However, the results predicted by the two methods become similar, and are exactly those given by the ground state phase diagram, for very low temperatures. On the other hand, the behavior of the local magnetizations as a function of the external magnetic field, shows that the transitions are of the first order type. $T_{L}^{s}$ and $T_{L}^{b}$ decrease when increasing the system size and/or the surface magnetic field. In particular, $T_{L}^{b}$ reaches the wetting temperature $T_{w}$ for sufficiently large system sizes.Comment: 11 Pages latex, 12 Figures P

Superfluid, Mott-Insulator, and Mass-Density-Wave Phases in the One-Dimensional Extended Bose-Hubbard Model

We use the finite-size density-matrix-renormalization-group (FSDMRG) method to obtain the phase diagram of the one-dimensional ($d = 1$) extended Bose-Hubbard model for density $\rho = 1$ in the $U-V$ plane, where $U$ and $V$ are, respectively, onsite and nearest-neighbor interactions. The phase diagram comprises three phases: Superfluid (SF), Mott Insulator (MI) and Mass Density Wave (MDW). For small values of $U$ and $V$, we get a reentrant SF-MI-SF phase transition. For intermediate values of interactions the SF phase is sandwiched between MI and MDW phases with continuous SF-MI and SF-MDW transitions. We show, by a detailed finite-size scaling analysis, that the MI-SF transition is of Kosterlitz-Thouless (KT) type whereas the MDW-SF transition has both KT and two-dimensional-Ising characters. For large values of $U$ and $V$ we get a direct, first-order, MI-MDW transition. The MI-SF, MDW-SF and MI-MDW phase boundaries join at a bicritical point at ($U, V) = (8.5 \pm 0.05, 4.75 \pm 0.05)$.Comment: 10 pages, 15 figure

Small-World Networks: Links with long-tailed distributions

Small-world networks (SWN), obtained by randomly adding to a regular structure additional links (AL), are of current interest. In this article we explore (based on physical models) a new variant of SWN, in which the probability of realizing an AL depends on the chemical distance between the connected sites. We assume a power-law probability distribution and study random walkers on the network, focussing especially on their probability of being at the origin. We connect the results to L\'evy Flights, which follow from a mean field variant of our model.Comment: 11 pages, 4 figures, to appear in Phys.Rev.