1 research outputs found
Self-Powered Nanocomposites under an External Rotating Magnetic Field for Noninvasive External Power Supply Electrical Stimulation
Electrical
stimulation in biology and gene expression has attracted
considerable attention in recent years. However, it is inconvenient
that the electric stimulation needs to be supplied an implanted power-transported
wire connecting the external power supply. Here, we fabricated a self-powered
composite nanofiber (CNF) and developed an electric generating system
to realize electrical stimulation based on the electromagnetic induction
effect under an external rotating magnetic field. The self-powered
CNFs generating an electric signal consist of modified MWNTs (m-MWNTs)
coated Fe<sub>3</sub>O<sub>4</sub>/PCL fibers. Moreover, the output
current of the nanocomposites can be increased due to the presence
of the magnetic nanoparticles during an external magnetic field is
applied. In this paper, these CNFs were employed to replace a bullfrog’s
sciatic nerve and to realize the effective functional electrical stimulation.
The cytotoxicity assays and animal tests of the nanocomposites were
also used to evaluate the biocompatibility and tissue integration.
These results demonstrated that this self-powered CNF not only plays
a role as power source but also can act as an external power supply
under an external rotating magnetic field for noninvasive the replacement
of injured nerve