BEING AGILE TO THRIVE AMIDST DISRUPTIVE DIGITAL INNOVATIONS

Firms around the world have been experiencing disruptive digital innovation. Such disruptionsaffect their business operations and models over time and geography. In this paper, we adopt Lucas and Goh’s (2009) framework of disruption responseto examine how do firms achieve agility in responding to disruptive digital innovation. The framework draws on dynamic capability theory, disruptive innovation concept, organizational agility concept and organizational core rigidity concept. This research-in-progress paper aims to conduct an in-depth case studyto understand how firms can be agile in responding to disruptive digital innovation. As a case study, this study adds to the growing corpus of literature on disruptive digital innovation. Theoretically, this study extends Lucas and Goh’s (2009) framework of disruption response, underpinning the advancement of knowledge in this area. The managerialinsights gleaned from this study can also guide firmsin being agile and thrive amidst disruptive digital innovations

Conflicts in Knowledge Management: Vistiting the Hidden Partner

As knowledge gains a reputation for being a critical resource in the information-intensive economy, organizations have doubled their efforts in trying to extract value from knowledge management policies. One particular aspect of knowledge management, which has gone unnoticed in academic research, is the presence of conflicts in knowledge activities. By adopting a conflict perspective of knowledge activities, this study arrives at a two-dimensional framework that defines knowledge conflicts in terms of its type and nature. Central to this paper is the fundamental idea that conflicts form an integral part of knowledge management and depending on how they are managed; conflicts may be formidable partners or dangerous adversaries in the corporate quest for knowledge-derived competitiveness

Escalated regeneration in sciatic nerve crush injury by the combined therapy of human amniotic fluid mesenchymal stem cells and fermented soybean extracts, Natto

Attenuation of inflammatory cell deposits and associated cytokines prevented the apoptosis of transplanted stem cells in a sciatic nerve crush injury model. Suppression of inflammatory cytokines by fermented soybean extracts (Natto) was also beneficial to nerve regeneration. In this study, the effect of Natto on transplanted human amniotic fluid mesenchymal stem cells (AFS) was evaluated. Peripheral nerve injury was induced in SD rats by crushing a sciatic nerve using a vessel clamp. Animals were categorized into four groups: Group I: no treatment; Group II: fed with Natto (16 mg/day for 7 consecutive days); Group III: AFS embedded in fibrin glue; Group IV: Combination of group II and III therapy. Transplanted AFS and Schwann cell apoptosis, inflammatory cell deposits and associated cytokines, motor function, and nerve regeneration were evaluated 7 or 28 days after injury. The deterioration of neurological function was attenuated by AFS, Natto, or the combined therapy. The combined therapy caused the most significantly beneficial effects. Administration of Natto suppressed the inflammatory responses and correlated with decreased AFS and Schwann cell apoptosis. The decreased AFS apoptosis was in line with neurological improvement such as expression of early regeneration marker of neurofilament and late markers of S-100 and decreased vacuole formation. Administration of either AFS, or Natto, or combined therapy augmented the nerve regeneration. In conclusion, administration of Natto may rescue the AFS and Schwann cells from apoptosis by suppressing the macrophage deposits, associated inflammatory cytokines, and fibrin deposits

Tunneling spectroscopy in the magnetic superconductor TmNi2B2C

We present new measurements about the tunneling conductance in the borocarbide superconductor TmNi$_2$B$_2$C. The results show a very good agreement with weak coupling BCS theory, without any lifetime broadening parameter, over the whole sample surface. We detect no particular change of the tunneling spectroscopy below 1.5K, when both the antiferromagnetic (AF) phase and the superconducting order coexist.Comment: Submitted to Phys. Rev. B, Rapid Communication

Comparison of Differential Pulse Voltammetry (DPV)-a new method of carbamazepine analysis-with Fluorescence Polarization Immunoassay (FPIA)

Carbamazepine is a widely used anti-epileptic drug with narrow therapeutic range. Many methods have been developed for monitoring the serum drug level. Differential pulse voltammetry (DPV), an electrochemical method advantaged by simple, inexpensive, and relatively short analysis time, has recently been developed for carbamazepine detection. We used a newly developed DPV method with glassy carbon as a working electrode to determine the carbamazepine level. The performance of DPV is compared with the widely used fluorescence polarization immunoassay (FPIA) technique in precision, accuracy, linearity and detection limit. The precision, linearity and accuracy of the DPV and FPIA techniques were comparable at most clinical used levels. The detection limit was 1 mu g/mL for the DPV technique and 0.5 mu g/mL for the FPIA technique. The performance of the DPV technique was within the FDA guidelines for bioanalytical methods, which ensures the clinical applicability of the DPV technique. The DPV technique may have the potential to be a good alternative for carbamazepine analysis

Quantum algebra in the mixed light pseudoscalar meson states

In this paper, we investigate the entanglement degrees of pseudoscalar meson states via quantum algebra Y(su(3)). By making use of transition effect of generators J of Y(su(3)), we construct various transition operators in terms of J of Y(su(3)), and act them on eta-pion-eta mixing meson state. The entanglement degrees of both the initial state and final state are calculated with the help of entropy theory. The diagrams of entanglement degrees are presented. Our result shows that a state with desired entanglement degree can be achieved by acting proper chosen transition operator on an initial state. This sheds new light on the connect among quantum information, particle physics and Yangian algebra.Comment: 9 pages, 3 figure

Spectrum of non-Hermitian heavy tailed random matrices

Let (X_{jk})_{j,k>=1} be i.i.d. complex random variables such that |X_{jk}| is in the domain of attraction of an alpha-stable law, with 0< alpha <2. Our main result is a heavy tailed counterpart of Girko's circular law. Namely, under some additional smoothness assumptions on the law of X_{jk}, we prove that there exists a deterministic sequence a_n ~ n^{1/alpha} and a probability measure mu_alpha on C depending only on alpha such that with probability one, the empirical distribution of the eigenvalues of the rescaled matrix a_n^{-1} (X_{jk})_{1<=j,k<=n} converges weakly to mu_alpha as n tends to infinity. Our approach combines Aldous & Steele's objective method with Girko's Hermitization using logarithmic potentials. The underlying limiting object is defined on a bipartized version of Aldous' Poisson Weighted Infinite Tree. Recursive relations on the tree provide some properties of mu_alpha. In contrast with the Hermitian case, we find that mu_alpha is not heavy tailed.Comment: Expanded version of a paper published in Communications in Mathematical Physics 307, 513-560 (2011

Elementary vortex pinning potential in a chiral p-wave superconductor

The elementary vortex pinning potential is studied in a chiral p-wave superconductor with a pairing d=z(k_x + i k_y) on the basis of the quasiclassical theory of superconductivity. An analytical investigation and numerical results are presented to show that the vortex pinning potential is dependent on whether the vorticity and chirality are parallel or antiparallel. Mutual cancellation of the vorticity and chirality around a vortex is physically crucial to the effect of the pinning center inside the vortex core.Comment: 4 pages, 4 figures include

Source size scaling of fragment production in projectile breakup

Fragment production has been studied as a function of the source mass and excitation energy in peripheral collisions of $^{35}$Cl+$^{197}$Au at 43 MeV/nucleon and $^{70}$Ge+$^{nat}$Ti at 35 MeV/nucleon. The results are compared to the Au+Au data at 600 MeV/nucleon obtained by the ALADIN collaboration. A mass scaling, by $A_{source} \sim$ 35 to 190, strongly correlated to excitation energy per nucleon, is presented, suggesting a thermal fragment production mechanism. Comparisons to a standard sequential decay model and the lattice-gas model are made. Fragment emission from a hot, rotating source is unable to reproduce the experimental source size scaling.Comment: 13 pages LaTeX file, including 3 postscript figures (in .tar.gz fornmat), accepted in Phys. Rev. C . Also available at http://thomson.phy.ulaval.ca/ions_lourds/gil-en.htm