59 research outputs found
Comparing spontaneous and pellet-triggered ELMs via non-linear extended MHD simulations
Injecting frozen deuterium pellets into an ELMy H-mode plasma is a well established scheme for triggering edge localized modes (ELMs) before they naturally occur. This paper presents non-linear simulations of spontaneous type-I ELMs and pellet-triggered ELMs in ASDEX Upgrade performed with the extended MHD code JOREK. A thorough comparison of the non-linear dynamics of these events is provided. In particular, pellet-triggered ELMs are simulated by injecting deuterium pellets into different time points during the pedestal build-up described in A Cathey et al (2020 Nuclear Fusion 60 124007). Realistic ExB and diamagnetic background plasma flows as well as the time dependent bootstrap current evolution are included during the build-up to accurately capture the balance between stabilising and destabilising terms for the edge instabilities. Dependencies on the pellet size and injection times are studied. The spatio-temporal structures of the modes and the resulting divertor heat fluxes are compared in detail between spontaneous and triggered ELMs. We observe that the premature excitation of ELMs by means of pellet injection is caused by a helical perturbation described by a toroidal mode number of n=1. In accordance with experimental observations, the pellet-triggered ELMs show reduced thermal energy losses and a narrower divertor wetted area with respect to spontaneous ELMs. The peak divertor energy fluence is seen to decrease when ELMs are triggered by pellets injected earlier during the pedestal build-up.</p
Probing non-linear MHD stability of the EDA H-mode in ASDEX Upgrade
Regimes of operation in tokamaks that are devoid of large ELMs have to be
better understood to extrapolate their applicability to reactor-relevant
devices. This paper describes non-linear extended MHD simulations that use an
experimental equilibrium from an EDA H-mode in ASDEX Upgrade. Linear ideal MHD
analysis indicates that the operational point lies slightly inside of the
stable region. The non-linear simulations with the visco-resistive extended MHD
code, JOREK, sustain non-axisymmetric perturbations that are linearly most
unstable with toroidal mode numbers of n = \{6 \dots 9\}, but non-linearly
higher and lower n become driven and the low-n become dominant. The poloidal
mode velocity during the linear phase is found to correspond to the expected
velocity for resistive ballooning modes. The perturbations that exist in the
simulations have somewhat smaller poloidal wavenumbers (k_{\theta} \sim 0.1 to
0.5 cm^{-1} ) than the experimental expectations for the quasi-coherent mode in
EDA, and cause non-negligible transport in both the heat and particle channels.
In the transition from linear to non-linear phase, the mode frequency chirps
down from approximately 35 kHz to 13 kHz, which corresponds approximately to
the lower end of frequencies that are typically observed in EDA H-modes in
ASDEX Upgrade
Autoregulation of Ribosome Biosynthesis by a Translational Response in Fission Yeast
Maintaining the appropriate balance between the small and large ribosomal subunits is critical for translation and cell growth. We previously identified the 40S ribosomal protein S2 (rpS2) as a substrate of the protein arginine methyltransferase 3 (RMT3) and reported a misregulation of the 40S/60S ratio in rmt3 deletion mutants of Schizosaccharomyces pombe. For this study, using DNA microarrays, we have investigated the genome-wide biological response of rmt3-null cells to this ribosomal subunit imbalance. Whereas little change was observed at the transcriptional level, a number of genes showed significant alterations in their polysomal-to-monosomal ratios in rmt3Δ mutants. Importantly, nearly all of the 40S ribosomal protein-encoding mRNAs showed increased ribosome density in rmt3 disruptants. Sucrose gradient analysis also revealed that the ribosomal subunit imbalance detected in rmt3-null cells is due to a deficit in small-subunit levels and can be rescued by rpS2 overexpression. Our results indicate that rmt3-null fission yeast compensate for the reduced levels of small ribosomal subunits by increasing the ribosome density, and likely the translation efficiency, of 40S ribosomal protein-encoding mRNAs. Our findings support the existence of autoregulatory mechanisms that control ribosome biosynthesis and translation as an important layer of gene regulation
Comparing spontaneous and pellet-triggered ELMs via non-linear extended MHD simulations
Injecting frozen deuterium pellets into an ELMy H-mode plasma is a well established scheme for triggering edge localized modes (ELMs) before they naturally occur. This paper presents non-linear simulations of spontaneous type-I ELMs and pellet-triggered ELMs in ASDEX Upgrade performed with the extended MHD code JOREK. A thorough comparison of the non-linear dynamics of these events is provided. In particular, pellet-triggered ELMs are simulated by injecting deuterium pellets into different time points during the pedestal build-up described in A Cathey et al (2020 Nuclear Fusion 60 124007). Realistic ExB and diamagnetic background plasma flows as well as the time dependent bootstrap current evolution are included during the build-up to accurately capture the balance between stabilising and destabilising terms for the edge instabilities. Dependencies on the pellet size and injection times are studied. The spatio-temporal structures of the modes and the resulting divertor heat fluxes are compared in detail between spontaneous and triggered ELMs. We observe that the premature excitation of ELMs by means of pellet injection is caused by a helical perturbation described by a toroidal mode number of n=1. In accordance with experimental observations, the pellet-triggered ELMs show reduced thermal energy losses and a narrower divertor wetted area with respect to spontaneous ELMs. The peak divertor energy fluence is seen to decrease when ELMs are triggered by pellets injected earlier during the pedestal build-up
Cofactor-independent antiphospholipid antibodies activate the NLRP3-inflammasome via endosomal NADPH-oxidase: implications for the antiphospholipid syndrome
Letter
A triggering mechanism responsible for the explosive onset of edge localised modes (ELMs) in fusion plasmas is identified by performing, for the first time, non-linear magnetohydrodynamic simulations of repetitive type-I ELMs. Briefly prior to the ELM crash, destabilising and stabilising terms are affected at different timescales by an increasingly ergodic magnetic field caused by non-linear interactions between the axisymmetric background plasma and growing non-axisymmetric perturbations. The separation of timescales prompts the explosive, i.e. faster than exponential, growth of an ELM crash which lasts ∼ 500μs. The duration and size of the simulated ELM crashes compare qualitatively well with type-I ELMs in ASDEX Upgrade. As expected for type-I ELMs, a direct proportionality between the heating power in the simulations and the ELM repetition frequency is obtained. The simulations presented here are a major step forward towards predictive modelling of ELMs and of the assessment of mitigation techniques in ITER and other future tokamaks
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