Study of an off-grid wireless sensors with Li-Ion battery and Giant Magnetostrisctive Material

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Multicomponent force transducer calibration procedure using tilted plates

The calibration of a multicomponent force transducers (MFTs)represents a challenge in the meganewtonrange. In fact,the generation of transversal forces and moments iscomplex since a force standard machine (FSM) is only able to apply an uniaxial force. Furthermore since MFTs are composed of multi-transducers, each one dedicated to a particular component, correlations between force and moment componentsare possible. Therefore, acalibration systemthat could simultaneously generate all force/moment components and could be suitableinevery FSMis needed. For this purpose, a coupleof tilted plates was designed. Calibration measurements were performed on a 2 MN MFT at INRiM, LNE and PTB. Exploitation matrixes and performance indicators showed good results, unless small but not negligible correlations between MFT outputs. In particularsome spurious valuesdue to the uncertainty inthe vertical force application pointinfluencedthe moment components

Dynamic Simulation of a Fe-Ga Energy Harvester Prototype Through a Preisach-Type Hysteresis Model

This paper presents the modeling of an Fe–Ga energy harvester prototype, within a large range of values of operating parameters (mechanical preload, amplitude and frequency of dynamic load, electric load resistance). The simulations, based on a hysteretic Preisach-type model, employ a voltage-driven finite element formulation using the fixed-point technique, to handle the material nonlinearities. Due to the magneto–mechanical characteristics of Fe–Ga, a preliminary tuning must be performed for each preload to individualize the fixed point constant, to ensure a good convergence of the method. This paper demonstrates how this approach leads to good results for the Fe–Ga prototype. The relative discrepancies between experimental and computational values of the output power remain lower than 5% in the entire range of operating parameters considered

Sequence-specific interactions of drugs interfering with the topoisomerase–DNA cleavage complex

AbstractDNA-processing enzymes, such as the topoisomerases (tops), represent major targets for potent anticancer (and antibacterial) agents. The drugs kill cells by poisoning the enzymes' catalytic cycle. Understanding the molecular details of top poisoning is a fundamental requisite for the rational development of novel, more effective antineoplastic drugs. In this connection, sequence-specific recognition of the top–DNA complex is a key step to preferentially direct the action of the drugs onto selected genomic sequences. In fact, the (reversible) interference of drugs with the top–DNA complex exhibits well-defined preferences for DNA bases in the proximity of the cleavage site, each drug showing peculiarities connected to its structural features. A second level of selectivity can be observed when chemically reactive groups are present in the structure of the top-directed drug. In this case, the enzyme recognizes or generates a unique site for covalent drug–DNA binding. This will further subtly modulate the drug's efficiency in stimulating DNA damage at selected sites. Finally, drugs can discriminate not only among different types of tops, but also among different isoenzymes, providing an additional level of specific selection. Once the molecular basis for DNA sequence-dependent recognition has been established, the above-mentioned modes to generate selectivity in drug poisoning can be rationally exploited, alone or in combination, to develop tailor-made drugs targeted at defined loci in cancer cells

Improving building envelope efficiency: interaction between embedded energy and operational energy

This study aims to evaluate the relationship between the carbon footprint produced by the energy improvement of the building envelope, assumed as the technological component that most affects the over-all energy performance of the building, and that embedded in the materials of which it is assembled. The purpose of this research is to observe the relationship between the reduction of impacts due to the operational phase and the variation of impacts incorporated in the materials and components used to obtain these benefits, including the effects induced in the overall environmental performance of the entire process

Selection rules for the orbital angular momentum of optically-produced THz radiation

In this work we theoretically study the transduction ofthe Orbital Angular Momentum (OAM)lfor infraredpump lasers into the THz domain. In the case of opti-cal rectification, the transduction of OAM occurs onlythrough a spin-orbit interaction, with the selection ruleon the OAMl=0valid for any kind of polarizationof the pump, which means that there is no transfer ofOAM along the propagation axis. In the difference fre-quency generation the selection rule for the difference∆lbetween the OAM of the pump fields with linear orcircular polarization isl=∆l, whereaslranges from∆l−2to∆l+2in both the cases of radial and azimuthalpolarization. Moreover, for THz generation in the lat-ter case, high diffraction obtained with tightly focusedpumps yieldsltending to∆l±2, whileltends to zeroin the opposite case of large pump beam

The Enactive Didactics for Enactive Mind:The Evolution of a Learning Model

The term "enactive mind " comes from the Varela work and the concept of "activation " underlines. Approach you enactive involves two concepts: from a side than the perception he consists in an action to his time driven by the perception coming from that action date and from the other but the cognitive structures they emerge from the recurring sensory- motor schemes which allow the action to be perceptively driven. In the specific one, approach him EM places like a frame to frame a series of phenomena considered essential for the comprehension of the concept of adaptation as social as the necessity of considering the relation world complexity as, the importing time constraints present in it, the nature and the modes in which mechanisms of this adaptation allow the formation of the social knowledge. In the EM approach the child "activates the social world " selectively perceiving it in the terms of what which is immediately essential for a social action, while the mental representations (the social knowledge) of this individualized world build themselves based on the repeated experiences ripened by these actions driven by the perception, become then deeply you root in the history of relational actions of the child to be tools for the adaptation to the world in which alive. The enactive vision, although it recalls in the meaning the concept of representation as mode to know, tries to exceed it in favor of the corporeality, that is an incorporate mind (embodied mind). A corollary of this theory is that subject

Effects due to the misalignment of build-up systems for force measurements in the Meganewton range

Calibration of force transducers in the Meganewton range is typically performed by comparison with reference build-up systems (BUS) under hydraulic presses for high loads. The centring of a BUS isa difficultoperation due to itsweight and dimension, andpossible misalignmentsand the resultingeffects are usually neglected.In this work the effect on force measurements due toa 3 mmmisalignment of a 3 MN BUS wasevaluated.Measurements were performed at INRiM and at LNE in hydraulic presses.Itis shown that the relative measurement errorsdue to misalignment were lowerthan the declared CMC uncertainty,thus the shiftof the BUSdid not influence the measurements

Multicomponent force transducer calibration procedure using tilted plates

The calibration of a multicomponent force transducers (MFTs)represents a challenge in the meganewtonrange. In fact,the generation of transversal forces and moments iscomplex since a force standard machine (FSM) is only able to apply an uniaxial force. Furthermore since MFTs are composed of multi-transducers, each one dedicated to a particular component, correlations between force and moment componentsare possible. Therefore, acalibration systemthat could simultaneously generate all force/moment components and could be suitableinevery FSMis needed. For this purpose, a coupleof tilted plates was designed. Calibration measurements were performed on a 2 MN MFT at INRiM, LNE and PTB. Exploitation matrixes and performance indicators showed good results, unless small but not negligible correlations between MFT outputs. In particularsome spurious valuesdue to the uncertainty inthe vertical force application pointinfluencedthe moment components