DenseBAM-GI: Attention Augmented DeneseNet with momentum aided GRU for HMER

The task of recognising Handwritten Mathematical Expressions (HMER) is crucial in the fields of digital education and scholarly research. However, it is difficult to accurately determine the length and complex spatial relationships among symbols in handwritten mathematical expressions. In this study, we present a novel encoder-decoder architecture (DenseBAM-GI) for HMER, where the encoder has a Bottleneck Attention Module (BAM) to improve feature representation and the decoder has a Gated Input-GRU (GI-GRU) unit with an extra gate to make decoding long and complex expressions easier. The proposed model is an efficient and lightweight architecture with performance equivalent to state-of-the-art models in terms of Expression Recognition Rate (exprate). It also performs better in terms of top 1, 2, and 3 error accuracy across the CROHME 2014, 2016, and 2019 datasets. DenseBAM-GI achieves the best exprate among all models on the CROHME 2019 dataset. Importantly, these successes are accomplished with a drop in the complexity of the calculation and a reduction in the need for GPU memory

A promising cognition boosting effect of leaves of Abrus precatorius

Objective: To assess the leaves of Abrus precatorius had earlier show cognition boosting effect against dementia in rodents. Methods: The methanol extract was fractionated into ethyl acetate and aqueous fractions and assessed for its nootropic and learning activity in albino rodents. The effect of triterpenoids containing ethylacetate soluble fraction of methanol extract significant enhancement in the retention ability of amnesic mice as compared to their respective controls using elevated plus maze and Cook and Weidley’s pole apparatus. Subsequently, the extracts were further studied for its in vitro acetylcholinesterase (AChE) inhibitory potential which can correlate with an improvement in cholinergic transmission. Piracetam was used as the standard drug while scopolamine hydrobromide served as the amnestic agent. Result: A.precatorius ethylacetate (APEA) soluble fraction of leaves produced a significant acquisition, retention and retrieval at dosed 150 and 300 mg/kg in interoceptive as well as exteroceptive memory models of rodents. While A.precatorius aqueous fraction (APAqs) of methanol extract not enhances both the acquisition as well as the retention of memory of learned task when administered at a dose of 300 mg/kg for a period of 7 days. It was found that APEA fraction potentially inhibits AChE with percentage inhibition of 91.33±0.33. Furthermore, both fraction were found safe with no deaths in mice treated orally with 2000 mg/kg. Conclusion: APEA showed to be a useful memory restorative agent in the treatment of dementia from the experiments performed. Keywords: Abrus precatorius, Piracetam, Scopolamine, Dementi

WOUND HEALING ACTIVITY OF BARRINGTONIA ACUTANGULA FRUIT EXTRACT

ABSTRACTObjective: To evaluate wound healing activity of methanolic extract of Barringtonia acutangula fruits (MEBA).Methods: Both excision and incision models were used in rats. In the excision wound model, the wound area of each animal was measured on days0, 2, 4, 6, 8, 10, 12, and 14 after inflicting the wound. Wound contraction (WC) was calculated as a percentage change in the initial wound size. Thehistopathology study of the skin (newly formed on the wounds) was carried out on the 12 post wounding day. In the incision wound model, thetensile strength was measured using tensiometer on the 14th post wounding day.thResults: MEBA at 20% w/w showed highly significant wound healing activity (p<0.01) as compared to control. The percentage of WC on the 14 dayby MEBA at 5%, 10%, and 20% w/w were found to be 93.86%, 93.86%, and 96.43%, respectively. There is increased the number of fibroblasts,increased collagen tissue and complete epithelialization in the case of MEBA ointment 20% w/w.Conclusion: MEBA fruit (ointment) showed significant wound healing activity in both excised wound model (20% w/w) and incision wound model(10% w/w) rats.Keywords: Barringtonia, Wound healing, Excision, Incision.t

Systemic Variety of Anaplastic Large - Cell Lymphoma

We present a case report of a patient with very aggressive course of anaplastic large-cell lymphoma. The patient had nonspecific complaints of easy fatigability and progressive breathlessness and had generalized lymphadenopathy. Initial investigations revealed pancytopenia. Bone marrow examination revealed presence of atypical cells. Liver biopsy showed portal tracts infiltrated by atypical lymphoid cells. Fine-needle aspiration of the lymph node finally confirmed anaplastic large-cell lymphoma. Patient succumbed to the illness

Enhancement of spin to charge conversion efficiency at the topological surface state by inserting normal metal spacer layer in the topological insulator based heterostructure

We report efficient spin to charge conversion (SCC) in the topological insulator (TI) based heterostructure ($BiSbTe_{1.5}Se_{1.5}/Cu/Ni_{80}Fe_{20}$) by using spin-pumping technique where $BiSbTe_{1.5}Se_{1.5}$ is the TI and $Ni_{80}Fe_{20}$ is the ferromagnetic layer. The SCC, characterized by inverse Edelstein effect length ($\lambda_{IEE}$) in the TI material gets altered with an intervening Copper (Cu) layer and it depends on the interlayer thickness. The introduction of Cu layer at the interface of TI and ferromagnetic metal (FM) provides a new degree of freedom for tuning the SCC efficiency of the topological surface states. The significant enhancement of the measured spin-pumping voltage and the linewidth of ferromagnetic resonance (FMR) absorption spectra due to the insertion of Cu layer at the interface indicates a reduction in spin memory loss at the interface that resulted from the presence of exchange coupling between the surface states of TI and the local moments of ferromagnetic metal. The temperature dependence (from 8K to 300K) of the evaluated $\lambda_{IEE}$ data for all the trilayer systems, TI/Cu/FM with different Cu thickness confirms the effect of exchange coupling between the TI and FM layer on the spin to charge conversion efficiency of the topological surface state

Electrophoretic Studies of Biologically Important Mixed Metal – Ascorbic Acid –Nitrilotriacetate Complexes

Quantitative indication of a complex formation comes from the estimation of the stability or formation constants characterizing the equilibria corresponding to the successive addition of ligands. The binary equilibria of metal (II) / (III)–ascorbic acid and also mixed equilibria metal (II) / (III)–ascorbic acid–NTA have been studied using ionophoretic technique. The stability constants of metal–ascorbic acid binary complexes are found to be 103.77, 102.47,102.27 and that of metal–ascorbic acid–NTA mixed complexes have been found to be 106.05, 105.93, 105.75, for Fe(III), Cu(II) and Co(II) complexes, respectively at 25 °C and ionic strength Ic = 0.1 mol dm–3 (HClO4). (doi: 10.5562/cca1778

Bioactive components from Gynandropsis gynandra leaves for antinociceptive activity

Gynandropsis gynandra Linn. (Capparadiaceae) leaves are used in the treatment of pain traditionally. In order to evaluate its scientific validity, leaves were extracted successively to produce various extracts. These extracts were screened for antinociceptive activity using hot plate test and acetic acid-induced writhing test in mice at the dose of 100 mg/kg, intraperitoneally. Aqueous extract was found most active in both the tests. Further it was fractionated into four major fractions and were screened by the same tests at the dose of 25 mg/kg, i.p. Results showed that AQI fraction is most active and may responsible for the antinociceptive action. GC-MS analysis of AQI fraction showed that it is a mixture of benzene acetic acid ethyl ester, octaneoic acid, dodecanal, and cholest-4-en-26-al, 3-oxo-, cyclic 26-(ethylene acetate).Colegio de Farmacéuticos de la Provincia de Buenos Aire

Bioactive components from Gynandropsis gynandra leaves for antinociceptive activity

Gynandropsis gynandra Linn. (Capparadiaceae) leaves are used in the treatment of pain traditionally. In order to evaluate its scientific validity, leaves were extracted successively to produce various extracts. These extracts were screened for antinociceptive activity using hot plate test and acetic acid-induced writhing test in mice at the dose of 100 mg/kg, intraperitoneally. Aqueous extract was found most active in both the tests. Further it was fractionated into four major fractions and were screened by the same tests at the dose of 25 mg/kg, i.p. Results showed that AQI fraction is most active and may responsible for the antinociceptive action. GC-MS analysis of AQI fraction showed that it is a mixture of benzene acetic acid ethyl ester, octaneoic acid, dodecanal, and cholest-4-en-26-al, 3-oxo-, cyclic 26-(ethylene acetate).Colegio de Farmacéuticos de la Provincia de Buenos Aire