Câncer de Próstata – Uma revisão sobre o seu rastreamento e diagnóstico / Prostate Câncer – A review of its screening and diagnosis

O Câncer de Próstata é o mais prevalente entre os homens no Brasil, atrás apenas do câncer de pele não melanoma; e o segundo em relação a mortalidade. Portanto, conhecer a doença, suas manifestações clínicas, seus fatores de risco e como é conduzido e feito seu diagnóstico é de extrema importância para a prática clínica. No presente trabalho, foi realizada uma revisão atual sobre a doença com ênfase em seu diagnóstico

Evidence of heat sensitivity in people with Parkinson’s disease

Examining how heat affects people with Parkinson’s disease is essential for informing clinical decision-making, safety, well-being, and healthcare planning. While there is evidence that the neuropathology associated with Parkinson’s disease affects thermoregulatory mechanisms, little attention has been given to the association of heat sensitivity to worsening symptoms and restricted daily activities in people with this progressive disease. Using a cross-sectional study design, we examined the experiences of people diagnosed with Parkinson’s disease in the heat. Two-hundred and forty-seven people completed an online survey (age: 66.0 ± 9.2 years; sex: male = 102 (41.3%), female = 145 (58.7%)), of which 195 (78.9%) reported becoming more sensitive to heat with Parkinson’s disease. Motor and nonmotor symptoms worsened with heat in 182 (73.7%) and 203 (82.2%) respondents, respectively. The most commonly reported symptoms to worsen included walking difficulties, balance impairment, stiffness, tremor, fatigue, sleep disturbances, excess sweating, difficulty concentrating, and light-headedness when standing. Concerningly, over half indicated an inability to work effectively in the heat, and nearly half reported that heat impacted their ability to perform household tasks and social activities. Overall, heat sensitivity was common in people with Parkinson’s disease and had a significant impact on symptomology, day-to-day activities and quality of life