Microwave irradiation and flow chemistry for a straightforward synthesis of piano-stool iron complexes

Two series of piano-stool iron(II) complexes bearing bidentate phosphine or mixed phosphoruse-nitrogen ligands have been prepared upon reaction with CpFe(CO)(2)I or [CpFe(naphthalene)][PF6] under microwave irradiation or using flow chemistry

Bifunctional (Cyclopentadienone) Iron-Tricarbonyl Complexes: Synthesis, Computational Studies and Application in Reductive Amination

Reductive amination under hydrogen pressure is a valuable process in organic chemistry to access amine derivatives from aldehydes or ketones. Knolker's complex has been shown to be an efficient iron catalyst in this reaction. To determine the influence of the substituents on the cyclopentadienone ancillary ligand, a series of modified Knolker's complexes was synthesised and fully characterised. These complexes were also transformed into their analogous acetonitrile iron-dicarbonyl complexes. Catalytic activities of these complexes were evaluated and compared in a model reaction. The scope of this reaction is also reported. For mechanistic insights, deuterium-labelling experiments and DFT calculations were undertaken and are also presented