353 research outputs found
The production of geosmin by Anabaena circinalis (Rabenhorst), and its measurement by sensory analysis
Thesis (M.Sc.)--University of Adelaide, Dept. of Botany, 199
Efeito de diferentes coberturas do solo sobre o desempenho da alface num sistema sob manejo orgânico.
Publicado também na: Revista Brasileira de Agroecologia, v. 2. n. 2, p. 563-866, out. 2007. (SEP 029)
Nível de adoção de boas práticas em sistemas de produção sob transição agroecológica no Sul de Mato Grosso do Sul.
bitstream/item/66257/1/31295.pdfOrganizado por: Alberto Feiden, Milton Parron Padovan, Adalgiza Inês Campolim, Aurélio Vinícius Borsato, Ivo de Sá Motta, João Batista Catto, Tércio Jacques Fehlauer
Lack of tolerance for the anti-dyskinetic effects of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, in rats
7-Nitroindazole (7-NI) inhibits neuronal nitric oxide synthase in vivo and reduces l-DOPA-induced dyskinesias in a rat model of parkinsonism. The aim of the present study was to determine if the anti-dyskinetic effect of 7-NI was subject to tolerance after repeated treatment and if this drug could interfere with the priming effect of l-DOPA. Adult male Wistar rats (200-250 g) with unilateral depletion of dopamine in the substantia nigra compacta were treated with l-DOPA (30 mg/kg) for 34 days. On the 1st day, 6 rats received ip saline and 6 received ip 7-NI (30 mg/kg) before l-DOPA. From the 2nd to the 26th day, all rats received l-DOPA daily and, from the 27th to the 34th day, they also received 7-NI before l-DOPA. Animals were evaluated before the drug and 1 h after l-DOPA using an abnormal involuntary movement scale and a stepping test. All rats had a similar initial motor deficit. 7-NI decreased abnormal involuntary movement induced by l-DOPA and the effect was maintained during the experiment before 7-NI, median (interquartile interval), day 26: 16.75 (15.88-17.00); day 28: 0.00 (0.00-9.63); day 29: 13.75 (2.25-15.50); day 30: 0.5 (0.00-6.25); day 31: 4.00 (0.00-7.13), and day 34: 0.5 (0.00-14.63), Friedman followed by Wilcoxon test,vs day 26, P < 0.05;. The response to l-DOPA alone was not modified by the use of 7-NI before the first administration of the drug (l-DOPA vs time interaction, F1,10 = 1.5, NS). The data suggest that tolerance to the anti-dyskinetic effects of a neuronal nitric oxide synthase inhibitor does not develop over a short-term period of repeated administration. These observations open a possible new therapeutic approach to motor complications of chronic l-DOPA therapy in patients with Parkinson’s disease
Estrutura da vegetação arbórea em um sistema agroflorestal no Município de Itaquiraí, MS, Brasil.
Fitossociologia do componente arbóreo de um sistema agroflorestal no Assentamento Lagoa Grande, Município de Dourados, MS.
Fitossociologia do componente arbóreo de um sistema agroflorestal no Município de Ponta Porã, MS.
Curso Superior de Tecnologia em Agroecologia em Mato Grosso do Sul: formação de profissionais para harmonizar o desenvolvimento à conservação e melhoria ambiental.
Produção de alimentos em sistemas agroflorestais de base agroecológica no cerrado na Região Sul de Mato Grosso do Sul.
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