Catheter Biopsy as a Useful Tool to Establish an Early Diagnosis for Canine Prostatic Disorders

In the study conducted on 29 pre-selected patients, we intended to evaluate the reproducibility of prostatic catheter biopsy (CB) as a minimally invasive procedure, directly comparing it to another well-established method, namely ultrasound-guided fine-needle aspiration biopsy (USG-FNAB). As a direct control we used histopathological evaluation and microbial cultivation of samples obtained by percutaneous Tru-Cut biopsy. Evaluating our data, we found that for establishing proper diagnosis by means of cytology, less invasive catheter biopsy (CB 75.86%) is at least comparable to already proven ultrasound-guided fine needle aspiration biopsy (USG-FNAB 72.41%), while catheter biopsy (CB 13 cases out of 29) was significantly (p < 0.0001) more sensitive in actual identification of infectious agents than ultrasound-guided fine needle aspiration biopsy (USG-FNAB 2 cases of 29).We believe that an early microbial evaluation of patients suffering from prostatic disorders helps to target antimicrobial treatment in the beginning of therapy, reducing the risk of failure due to bacterial resistance

Geoinformatics and Crowdsourcing in Cultural Heritage: A Tool for Managing Historical Archives

Archives of historical photographs have a great potential for "geo- or spatial sciences", for they can provide highly relevant visual data on historical landscapes, populated places and settlement structures, including those now destroyed. Processing of these archives represents many challenges, among them the application of geoinformatic concepts and information technologies. The article presents the example of geo-referencing, crowdsourcing, and other computer-based technologies applied to the archival photographs of today-destroyed sites on the Czech – Bavarian border, where many villages, farm sites and monuments were destroyed in the 1950s or abandoned as a consequence of post-WWII development. In the situation of dramatically changing landscape and land use, historical photographs are an important source of documentation for both research and virtual reconstruction of disappeared places, landscape, and society