The “Noble Method®”: A One Health Approach for a Sustainable Improvement in Dairy Farming

The Noble Method® has been successfully introduced in the last few years in Italy and in some foreign countries. This novel livestock management provides, among other rules, a high forage/concentrate ratio, no use of silage and supplements, no GMOs and the availability of outdoor paddocks. One of the goals is to achieve high-quality milk in terms of nutritional properties. Other benefits have been reported; amongst them, the forage/concentrate ratio of the diet was shown to reduce the amount of methane produced by animals, also, the system provides economic benefits, mainly for small breeders, in terms of the sustainability and market placement of milk. Thus, the method represents a sustainable approach to improve the production and the supply chain, from the land to the final product. In this review, the most recent studies on Noble Method® are depicted, showing that, besides the nutritional proprieties of dairy products, the method is able to improve animal welfare, human health and environmental sustainability, thus falling within a “One Health” approach

Mycobacterium xenopi pulmonary infection resulting in self-limited immune reconstitution inflammatory syndrome in an HIV-1 infected patient

Highly active antiretroviral therapy (HAART) has been shown to induce a major and durable viral load reduction accompanied by a stable CD4 increase. This process may evolve with adverse clinical phenomena, known as the immune reconstitution inflammatory syndrome (IRIS). In the HIV population, non-tuberculous mycobacteria are a common cause of IRIS. However, only a few cases of Mycobacterium xenopi associated IRIS have been described. This paper concerns a case of M. xenopi pulmonary infection resulting in self-limited immune reconstitution inflammatory syndrome in an HIV-1 infected patient

Visceral leishmaniasis in a patient with common variable immunodeficiency and evans syndrome: clinical remarks

Visceral Leishmaniasis (VL) is a vector-borne zoonosis endemic in Southern Italy whose usual clinical features include fever, splenomegaly, pancytopenia and hypergammaglobulinemia. The clinical and biochemical picture may be misleading in patients with immunodeficiency diseases hampering the diagnosis. We describe a VL case in a patient whose spleen had been removed and who had Common Variable Immunodeficiency and Evans syndrome

Infected atrial myxoma: case report and literature review

Myxoma is the most common type of cardiac tumour in all age groups. It may simulate infective endocarditis but is rarely infected. We describe one case of infected left atrial myxoma caused by Enterococcus faecalis. Combined therapy, consisting of surgical management and antimicrobial therapy, was used. Histological examination of the excised tumour revealed a typical myxoma with infiltrates of neutrophils. Few cases of infected atrial myxomas have been reported in the literature