383 research outputs found

    Quality of life (QoL) in southern Chinese with systemic lupus erythematosus (SLE)

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    Temporal variability and social heterogeneity in disease transmission: The case of SARS in Hong Kong

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    The extent to which self-adopted or intervention-related changes in behaviors affect the course of epidemics remains a key issue for outbreak control. This study attempted to quantify the effect of such changes on the risk of infection in different settings, i.e., the community and hospitals. The 2002-2003 severe acute respiratory syndrome (SARS) outbreak in Hong Kong, where 27% of cases were healthcare workers, was used as an example. A stochastic compartmental SEIR (susceptible-exposed-infectious-removed) model was used: the population was split into healthcare workers, hospitalized people and general population. Super spreading events (SSEs) were taken into account in the model. The temporal evolutions of the daily effective contact rates in the community and hospitals were modeled with smooth functions. Data augmentation techniques and Markov chain Monte Carlo (MCMC) methods were applied to estimate SARS epidemiological parameters. In particular, estimates of daily reproduction numbers were provided for each subpopulation. The average duration of the SARS infectious period was estimated to be 9.3 days (±0.3 days). The model was able to disentangle the impact of the two SSEs from background transmission rates. The effective contact rates, which were estimated on a daily basis, decreased with time, reaching zero inside hospitals. This observation suggests that public health measures and possible changes in individual behaviors effectively reduced transmission, especially in hospitals. The temporal patterns of reproduction numbers were similar for healthcare workers and the general population, indicating that on average, an infectious healthcare worker did not infect more people than any other infectious person. We provide a general method to estimate time dependence of parameters in structured epidemic models, which enables investigation of the impact of control measures and behavioral changes in different settings. © 2009 Cori et al.published_or_final_versio

    Cervical dysplasia in patients with systemic lupus erythematosus

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    Integrative Eastern Body-mind-spirit healing - arts and science of acceptance and transformation of pain and suffering

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    Special PresentationDisease, frailty, disability and dying are painful, stressful, uncomfortable, and agitating. Despite old age and death are inevitable processes in living, people do hope that one can stay young, energetic, cheerful and happy all the time besides enjoying longevity. Western positivistic treatment focuses on an antagonistic stance of fighting the disease and treats illness as an enemy. Eastern integrative healing philosophy emphasizes on holistic harmonization of bodily strengths and energies. Ill health is seen as system imbalance which can be restored. Endurance of pain and suffering are seen as virtues in life. A reflective mechanism of acceptance can help foster a process of transformation from pain and suffering into enlightenment and peace of mind. This presentation will share arts and science of an integrative eastern body-mind-spirit healing in Hong Kong.published_or_final_versio

    Implementing Effective Group Work for Mathematical Achievement in Primary School Classrooms in Hong Kong

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    The Hong Kong Education Bureau recommends that primary school pupils’ mathematical achievement be enhanced via collaborative discussions engendered by group work. This pedagogic change may be hindered by Confucian heritage classroom practices and Western-dominated group work approaches that predominate in Hong Kong. To overcome these obstacles, we introduced a relational approach to group work in a quasi-experimental study. Our sample included 20 teachers randomly allocated to experimental (12) and control (8) conditions and their 504 mathematics pupils (aged 9–10). The relational approach focused on the development of peer relationships in a culturally appropriate manner and was implemented over 7 months. Pupils were pre-/post-tested for mathematical achievement and systematically observed, and the teachers were assessed for subject knowledge and pre-/post-tested for pedagogic efficacy. Analysis of covariance (ANCOVA) and hierarchical linear modeling (HLM) results show enhanced mathematical achievement, supported by improved peer-based communication skills and time-on-task for the experimental pupils. Experimental teachers raised their pedagogic efficacy. Results indicate the potential of the relational approach for boosting academic achievement via enhanced child-peer-teacher interaction and the need to reassess the role of peer-based latent collectivist learning in Confucian heritage classrooms.postprin

    Sex hormones and apoptosis and immunoglobulin production in systemic lupus erythematosus

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    BACKGROUND: SLE is an autoimmune disease that affects predominantly female of reproductive age. Previous studies have suggested an immunomodulatory role of sex hormones in the pathogenesis of SLE. Objectives: To examine the effects of various sex hormones on apoptosis and immunoglobulin production by peripheral blood mononuclear cells (PBMCs) in SLE patients …published_or_final_versio

    Toxicity of ZnO and TiO<font size=-1><sub>2</sub></font> to Escherichia coli cells

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    Complete Genome Sequence for Treponema sp. OMZ 838 (ATCC 700772, DSM 16789), Isolated from a Necrotizing Ulcerative Gingivitis Lesion

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    The oral treponeme bacterium Treponema sp. OMZ 838 was originally isolated from a human necrotizing ulcerative gingivitis (NUG) lesion. Its taxonomic status remains uncertain. The complete genome sequence length was determined to be 2,708,067 bp, with a G+C content of 44.58%, and 2,236 predicted coding DNA sequences (CDS)
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