DC field induced enhancement and inhibition of spontaneous emission in a cavity

We demonstrate how spontaneous emission in a cavity can be controlled by the application of a dc field. The method is specially suitable for Rydberg atoms. We present a simple argument for the control of emission.Comment: 3-pages, 2figure. accepted in Phys. Rev.

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway

Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown mechanisms. Here, we investigated how the FA composition of CMRs influences their actions on human aortic endothelial cells (HAECs) by comparing the effects of model CMRs—artificial TG-rich CMR-like particles (A-CRLPs)—containing TGs extracted from fish, DHA-rich algal, corn, or palm oils. HAECs responded with distinct transcriptional programs according to A-CRLP TG content and oxidation status, with genes involved in antioxidant defense and cytoprotection most prominently affected by n-3 PUFA-containing A-CRLPs. These particles were significantly more efficacious inducers of heme oxygenase-1 (HO-1) than n-6 PUFA corn or saturated FA-rich palm CRLPs. Mechanistically, HO-1 induction by all CRLPs requires NADPH oxidase 4, with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species. Activation of both p38 MAPK and PPARβ/δ culminates in increased nuclear factor erythroid 2-related factor 2 (Nrf2) expression/nuclear translocation and HO-1 induction. These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2-dependent HO-1 expression and may represent key mechanisms through which dietary FAs differentially impact progression of endothelial dysfunction

Current noise of a quantum dot p-i-n junction in a photonic crystal

The shot-noise spectrum of a quantum dot p-i-n junction embedded inside a three-dimensional photonic crystal is investigated. Radiative decay properties of quantum dot excitons can be obtained from the observation of the current noise. The characteristic of the photonic band gap is revealed in the current noise with discontinuous behavior. Applications of such a device in entanglement generation and emission of single photons are pointed out, and may be achieved with current technologies.Comment: 4 pages, 3 figures, to appear in Phys. Rev. B (2005

High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial

Background: Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are unclear. Objectives: The primary objective was to determine the vascular effects of EPA + DHA compared with DHA only during postprandial lipemia relative to control high–oleic acid meals; the secondary objective was to characterize the effects of linoleic acid–enriched high-fat meals relative to the control meal. Design: We conducted a randomized, controlled, double-blind crossover trial of 4 high-fat (75-g) meals containing 1) high–oleic acid sunflower oil (HOS; control), 2) HOS + fish oil (FO; 5 g EPA and DHA), 3) HOS + algal oil (AO; 5 g DHA), and 4) high–linoleic acid sunflower oil (HLS) in 16 healthy men (aged 35–70 y) with higher than optimal fasting triacylglycerol concentrations (mean ± SD triacylglycerol, 1.9 ± 0.5 mmol/L). Results: Elevations in triacylglycerol concentration relative to baseline were slightly reduced after FO and HLS compared with the HOS control (P < 0.05). The characteristic decrease from baseline in plasma nonesterified fatty acids after a mixed meal was inhibited after AO (Δ 0–3 h, P < 0.05). HLS increased the augmentation index compared with the other test meals (P < 0.05), although the digital volume pulse–reflection index was not significantly different. Plasma 8-isoprostane F(2α) analysis revealed opposing effects of FO (increased) and AO (reduced) compared with the control (P < 0.05). No differences in nitric oxide metabolites were observed. Conclusions: These data show differential postprandial 8-isoprostane F(2α) responses to high-fat meals containing EPA + DHA–rich fish oil compared with DHA-rich AO, but these differences were not associated with consistent effects on postprandial vascular function or lipemia. More detailed analyses of polyunsaturated fatty acid–derived lipid mediators are required to determine possible divergent functional effects of single meals rich in either DHA or EPA. This trial was registered at clinicaltrials.gov as NCT01618071

A survey for redshifted molecular and atomic absorption lines - II. Associated HI, OH and millimetre lines in the z >~ 3 Parkes quarter-Jansky flat-spectrum sample

We present the results of a z>2.9 survey for HI 21-cm and molecular absorption in the hosts of radio quasars using the GMRT and the Tidbinbilla 70-m telescope. Previously published searches, which are overwhelmingly at redshifts of z<1, exhibit a 42% detection rate (31 out of 73 sources), and the inclusion of our survey yields a 17% detection rate (2 out of 12 sources) at z>2.5. We therefore believe that our high redshift selection is responsible for our exclusive non-detections, and find that at ultra-violet luminosities of >10e23 W/Hz, 21-cm absorption has never been detected. We also find this to not only apply to our targets, but also those at low redshift exhibiting similar luminosities, giving zero detections out of a total of 16 sources over z=0.24 to 3.8. This is in contrast to the < 10e23 W/Hz sources where there is a near 50% detection rate of 21-cm absorption. The mix of 21-cm detections and non-detections is currently attributed to orientation effects, where according to unified schemes of active galactic nuclei, 21-cm absorption is more likely to occur in sources designated as radio galaxies (type-2 objects, where the nucleus is viewed through dense obscuring circumnuclear gas) than in quasars(type-1 objects, where we have a direct view to the nucleus). However, due to the exclusively high ultra-violet luminosities of our targets it is not clear whether orientation effects alone can wholly account for the distribution, although there exists the possibility that the large luminosities are indicative of a changing demographic of galaxy types. We also find that below luminosities of ~10e23 W/Hz, both type-1 and type-2 objects have a 50% likelihood of exhibiting 21-cm absorption.Comment: 21 pages, accepted by MNRA

A Simplest Swimmer at Low Reynolds Number: Three Linked Spheres

We propose a very simple one-dimensional swimmer consisting of three spheres that are linked by rigid rods whose lengths can change between two values. With a periodic motion in a non-reciprocal fashion, which breaks the time-reversal symmetry as well as the translational symmetry, we show that the model device can swim at low Reynolds number. This model system could be used in constructing molecular-size machines

Inertial Focusing of Particles in Curved Micro-channels

Inertial focusing is the migration of particles in flow laterally across a channel into well-defined equilibrium positions. In microfluidic channels, inertial focusing takes advantage of hydrodynamic interactions even at high flow speeds. Particle isolation through inertial focusing is a high throughput method of processing biological samples for point-of-care diagnostics. While photos provide qualitative analyses of inertial focusing, we desired quantitative characterization of these systems. In this study, we ran flow experiments, first with fluorescent polystyrene beads and later with cells in solution, through curved micro-channels at controlled rates using a syringe pump. Our results from polystyrene bead experiments confirmed previous studies on flow through curved micro-channels, in which particles are focused along both sides of the channel at low flow rates and transition towards the center of the channel as the flow rate increases. FWHM analysis also showed that the streamline width is minimized at an intermediate flow rate, indicating inertial focusing is optimized under that condition. As this method of analysis was confirmed with polystyrene beads, we further used this analysis method to characterize the focusing of cells in solution. To maximize both throughput and purity, microfluidic devices must be designed to operate at the highest flow rate at which effective separation from bulk fluid can occur. The device presented in this report indeed isolates the desired target cells to be studied in downstream characterization.http://deepblue.lib.umich.edu/bitstream/2027.42/169578/1/Honors_Capstone_Anna_Kaehr.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/169578/2/Kaehr_Anna_Capstone_Poster.pptxhttp://deepblue.lib.umich.edu/bitstream/2027.42/169578/3/Capstone_Presentation_Video_Anna_Kaehr.mp

A-Polynomials of fillings of the Whitehead sister

Knots obtained by Dehn filling the Whitehead sister link include some of the smallest volume twisted torus knots. Here, using results on A-polynomials of Dehn fillings, we give formulas to compute the A-polynomials of these knots. Our methods also apply to more general Dehn fillings of the Whitehead sister link complement.Comment: 15 pages, 11 figure

Magnetic field induced lattice anomaly inside the superconducting state of CeCoIn5_5: evidence of the proposed Fulde-Ferrell-Larkin-Ovchinnikov state

We report high magnetic field linear magnetostriction experiments on CeCoIn$_5$ single crystals. Two features are remarkable: (i) a sharp discontinuity in all the crystallographic axes associated with the upper superconducting critical field $B_{c2}$ that becomes less pronounced as the temperature increases; (ii) a distinctive second order-like feature observed only along the c-axis in the high field (10 T $\lesssim B \leq B_{c2}$) low temperature ($T \lesssim$ 0.35 K) region. This second order transition is observed only when the magnetic field lies within 20$^o$ of the ab-planes and there is no signature of it above $B_{c2}$, which raises questions regarding its interpretation as a field induced magnetically ordered phase. Good agreement with previous results suggests that this anomaly is related to the transition to the Fulde-Ferrel-Larkin-Ovchinnikov superconducting state.Comment: 3 figures, 5 page