8 research outputs found
First translational ‘Think Tank’ on cerebrovascular disease, cognitive impairment and dementia
Full text linkNeural mechanisms underlying the higher levels of subjective well-being in extraverts: Pleasant bias and unpleasant resistance
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Adaptive immunity against gut microbiota enhances apoE-mediated immune regulation and reduces atherosclerosis and western-diet-related inflammation
No full textTargeting the adaptive immune system: new strategies in the treatment of atherosclerosis
No full textAtherosclerosis is a lipid-driven chronic inflammatory disease of the arterial wall. Current treatment of atherosclerosis is focused on limiting its risk factors, such as hyperlipidemia or hypertension. However, treatments that target the inflammatory nature of atherosclerosis are still under development. Discovery of novel targets involved in the inflammation of the arterial wall creates opportunities to design new therapeutics that successfully modulate atherosclerosis. Here, we review drug targets that have proven to play pivotal roles in the adaptive immune system in atherosclerosis, and we discuss their potential as novel therapeutic
