EVALUATION OF EFFICACY AND TOXICITY OF DIFFERENT TREATMENT REGIMENS IN PLASMODIUM FALCIPARUM MALARIA

The efficacy and toxicity of four commonly used antimalarials was evaluated. Thecombinations evaluated were Artesunate and Doxycycline, Quinine and Doxycycline, Artesunateand Quinine, Artesunate and Mefloquine. The four combinations did not show any statisticallysignificant difference in terms of days of defervescence, parasite clearance and hospital stay. Allthe four combinations were well tolerated