18 research outputs found

    Wastewater-based epidemiology in hazard forecasting and early-warning systems for global health risks

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    With the advent of the SARS-CoV-2 pandemic, Wastewater-Based Epidemiology (WBE) has been applied to track community infection in cities worldwide and has proven succesful as an early warning system for identification of hotspots and changingprevalence of infections (both symptomatic and asymptomatic) at a city or sub-city level. Wastewater is only one of environmental compartments that requires consideration. In this manuscript, we have critically evaluated the knowledge-base and preparedness for building early warning systems in a rapidly urbanising world, with particular attention to Africa, which experiences rapid population growth and urbanisation. We have proposed a Digital Urban Environment Fingerprinting Platform (DUEF) – a new approach in hazard forecasting and early-warning systems for global health risks and an extension to the existing concept of smart cities. The urban environment (especially wastewater) contains a complex mixture of substances including toxic chemicals, infectious biological agents and human excretion products. DUEF assumes that these specific endo- and exogenous residues, anonymously pooled by communities’ wastewater, are indicative of community-wide exposure and the resulting effects. DUEF postulates that the measurement of the substances continuously and anonymously pooled by the receiving environment (sewage, surface water, soils and air), can provide near real-time dynamic information about the quantity and type of physical, biological or chemical stressors to which the surveyed systems are exposed, and can create a risk profile on the potential effects of these exposures. Successful development and utilisation of a DUEF globally requires a tiered approach including: Stage I: network building, capacity building, stakeholder engagement as well as a conceptual model, followed by Stage II: DUEF development, Stage III: implementation, and Stage IV: management and utilization. We have identified four key pillars required for the establishment of a DUEF framework: (1) Environmental fingerprints, (2) Socioeconomic fingerprints, (3) Statistics and modelling and (4) Information systems. This manuscript critically evaluates the current knowledge base within each pillar and provides recommendations for further developments with an aim of laying grounds for successful development of global DUEF platforms

    Investigation of an outbreak of <I>Serratia marcescens </I>on the neonatal and paediatric platform

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    Please help populate SUNScholar with the full text of SU research output. Also - should you need this item urgently, please send us the details and we will try to get hold of the full text as quick possible. E-mail to [email protected]. Thank you.Geneeskunde en GesondheidswetenskappeGemeenskapsgesondhei

    Creating functional and sustainable School–Community Partnerships: Lessons from three South African cases

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    Globally, there is agreement that school–community partnerships are one of the mechanisms to address challenges that schools cannot address alone. However, evidence suggests that where school–community partnerships have been initiated, their functionality and continuity is not always easy to achieve, and research locally and internationally has not sufficiently addressed this concern. To bridge this gap, guided by Epstein’s theory of overlapping spheres of influence, this paper examined what makes school–community partnerships functional and sustainable. The research used a qualitative case study and employed discursive oriented interviews (both individual and focus group), a researcher’s reflective journal, and document reviews to generate the data. Participants were principals, teachers, and academics from two universities. It was found that for partnerships to be functional and sustainable there is a need to ensure that there is collaborative planning and decision-making, effective two-way communication, eagerness to address power issues, and the creation of a culture that promotes participative leadership. From these findings, the paper concludes that principal’s leadership is only critical at the beginning stage of partnerships, and teacher leadership is central in the functionality and continuity of partnerships. In relation to the theoretical framework, it is further concluded that power is an important element to consider, which either brings partners together or pushes them apart.http://journals.sagepub.com/home/emahj2020Education Management and Policy Studie

    Pharmacology of Acetylcholine and Cholinergic Receptors

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