18 research outputs found
Achievable rates optimization for broadcast channels using finite size constellations under transmission constraints
Effective Capacity in Broadcast Channels with Arbitrary Inputs
We consider a broadcast scenario where one transmitter communicates with two
receivers under quality-of-service constraints. The transmitter initially
employs superposition coding strategies with arbitrarily distributed signals
and sends data to both receivers. Regarding the channel state conditions, the
receivers perform successive interference cancellation to decode their own
data. We express the effective capacity region that provides the maximum
allowable sustainable data arrival rate region at the transmitter buffer or
buffers. Given an average transmission power limit, we provide a two-step
approach to obtain the optimal power allocation policies that maximize the
effective capacity region. Then, we characterize the optimal decoding regions
at the receivers in the space spanned by the channel fading power values. We
finally substantiate our results with numerical presentations.Comment: This paper will appear in 14th International Conference on
Wired&Wireless Internet Communications (WWIC
Multi-destination aggregation with binary symmetric broadcast channel based coding in 802.11 WLANs
Interference cancellation for non-orthogonal multiple access used in future wireless mobile networks
Prevalence of Bartonella henselae and Bartonella clarridgeiae in cats in the south of Brazil: a molecular study
TBK1 mutation spectrum in an extended European patient cohort with frontotemporal dementia and amyotrophic lateral sclerosis
We investigated the mutation spectrum of the TANK-Binding Kinase 1 (TBK1) gene and its associated phenotypic spectrum by exonic resequencing of TBK1 in a cohort of 2,538 patients with frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), or FTD plus ALS, ascertained within the European Early-Onset Dementia Consortium. We assessed pathogenicity of predicted protein-truncating mutations by measuring loss of RNA expression. Functional effect of in-frame amino acid deletions and missense mutations was further explored in vivo on protein level and in vitro by an NFκB-induced luciferase reporter assay and measuring phosphorylated TBK1. The protein-truncating mutations led to the loss of transcript through nonsense-mediated mRNA decay. For the in-frame amino acid deletions, we demonstrated loss of TBK1 or phosphorylated TBK1 protein. An important fraction of the missense mutations compromised NFκB activation indicating that at least some functions of TBK1 are lost. Although missense mutations were also present in controls, over three times more mutations affecting TBK1 functioning were found in the mutation fraction observed in patients only, suggesting high-risk alleles (P = 0.03). Total mutation frequency for confirmed TBK1 LoF mutations in the European cohort was 0.7%, with frequencies in the clinical subgroups of 0.4% in FTD, 1.3% in ALS, and 3.6% in FTD-ALS