Desenvolvimento de revestimentos poliméricos para liberação controlada de ureia.

Entrada padronizada: RIBEIRO, C

Methods and application in experimental pharmacology and drug discovery: 2021

Searching for new drugs is an expensive and time-consuming process, but it remains vital for the treatment of many old and new diseases. The availability of current advanced technologies has led to an acceleration of the drug discovery process, facilitating further development of personalized therapies. Sometimes, to obtain the desired therapeutic goals, the drug administration strategy can be of primary importance. Equally important, however, is the understanding of the complex mechanisms of action of new drugs on different cellular and molecular targets, both when the drugs are used alone and when they are administered in combination with other molecules

Google haul out : Earth observation imagery and digital aerial surveys in coastal wildlife management and abundance estimation

© The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Bioscience 67 (2017): 760–768, doi:10.1093/biosci/bix059.As the sampling frequency and resolution of Earth observation imagery increase, there are growing opportunities for novel applications in population monitoring. New methods are required to apply established analytical approaches to data collected from new observation platforms (e.g., satellites and unmanned aerial vehicles). Here, we present a method that estimates regional seasonal abundances for an understudied and growing population of gray seals (Halichoerus grypus) in southeastern Massachusetts, using opportunistic observations in Google Earth imagery. Abundance estimates are derived from digital aerial survey counts by adapting established correction-based analyses with telemetry behavioral observation to quantify survey biases. The result is a first regional understanding of gray seal abundance in the northeast US through opportunistic Earth observation imagery and repurposed animal telemetry data. As species observation data from Earth observation imagery become more ubiquitous, such methods provide a robust, adaptable, and cost-effective solution to monitoring animal colonies and understanding species abundances.We would like to thank generous support from International Fund for Animal Welfare, the Bureau of Ocean Energy, and the Oak Foundation for funding support for the telemetry devices