13 research outputs found

    Frequency control ancillary service provided by a wind farm: dual-BESS scheme

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    © 2014, The Author(s). Network frequency control function is incorporated into a grid-connected wind farm-dual battery energy storage system (BESS) scheme. The design of the scheme takes advantage of the rapid response characteristics of the BESS and the in-built short-term overloading capability of the associated power conversion devices. A control strategy to regulate the BESS output power is then proposed. It is shown that the frequency control action offered by the BESS complements amicably with that of conventional generators in enhancing the frequency regulation attribute of the grid system

    Genome-wide association study identifies five loci associated with lung function

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    Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) in the SpiroMeta consortium (n = 20,288 individuals of European ancestry). We conducted a meta-analysis of top signals with data from direct genotyping (n ≤ 32,184 additional individuals) and in silico summary association data from the CHARGE Consortium (n = 21,209) and the Health 2000 survey (n ≤ 883). We confirmed the reported locus at 4q31 and identified associations with FEV1 or FEV1/FVC and common variants at five additional loci: 2q35 in TNS1 (P = 1.11 × 10−12), 4q24 in GSTCD (2.18 × 10−23), 5q33 in HTR4 (P = 4.29 × 10−9), 6p21 in AGER (P = 3.07 × 10−15) and 15q23 in THSD4 (P = 7.24 × 10−15). mRNA analyses showed expression of TNS1, GSTCD, AGER, HTR4 and THSD4 in human lung tissue. These associations offer mechanistic insight into pulmonary function regulation and indicate potential targets for interventions to alleviate respiratory disease.peerReviewe
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