10 research outputs found
Angora goat gastrointestinal parasite knowledge and control practices among Lesotho farming communities
Attitudes and practices of resource-limited farmers on the control of gastrointestinal nematodes in goats foraging in grasslands and forestlands
Immunoglobulins as Biomarkers for Gastrointestinal Nematodes Resistance in Small Ruminants: A systematic review
The rise of anthelmintic resistance worldwide has led to the development of alternative control strategies for gastrointestinal nematodes (GIN) infections, which are one of the main constraints on the health of grazing small ruminants. Presently, breeding schemes rely mainly on fecal egg count (FEC) measurements on infected animals which are time-consuming and requires expertise in parasitology. Identifying and understanding the role of immunoglobulins in the mechanisms of resistance could provide a more efficient and sustainable method of identifying nematode-resistant animals for selection. In this study we review the findings on immunoglobulin response to GIN in the literature published to date (june 2019) and discuss the potential to use immunoglobulins as biomarkers. The literature review revealed 41 studies which measured at least one immunoglobulin: 35 focused on lamb immune response (18 used non-naive lambs) and 7 on yearlings. In this review we propose a conceptual model summarizing the role of immunoglobulins in resistance to GIN. We highlight the need for more carefully designed and documented studies to allow comparisons across different populations on the immunoglobulin response to GIN infection
Assessment of Haemonchus contortus larval and adult somatic antigens in sero-diagnosis of haemonchosis in naturally infected sheep and goats
Differences in immune responses to Haemonchus contortus infection in the susceptible Ile de France and the resistant Santa Ines sheep under different anthelmintic treatments regimens
Positive selection and climatic effects on MHC class II gene diversity in hares (Lepus capensis) from a steep ecological gradient
Immunity to gastrointestinal nematodes in ruminants: effector cell mechanisms and cytokines
Natural compounds extracted from Moringa oleifera and their agricultural applications
Natural bio-active compounds synthesized by plants as secondary metabolites are well known and established. Today, their application in various fields such as medicine in the form of drugs and biopesticides in agriculture is well documented. In recent times, the delivery of such compounds is achieved through nanodelivery technology, which is gaining acceptability in both field of drugs and agrochemical industries. The bio-active compounds with chemical diversity are obtained from nature either as homogenous plant crude extracts or as purified compounds. Crude plant extracts exist as a combination of different bio-active compounds with various polarities, and their partition remains a challenge in the process of characterization and identification. Extraction of these compounds from plant species is achieved by different solvents and extraction methods. Analytical methods like HPLC have commonly been utilized with GC-MS and LC-MS/MS chromatography methods to identify the compounds. Crude extracts from different morphological parts of plant species including Moringa oleifera are increasingly becoming important in the context of agricultural pest management and human medicine. M. oleifera is a medicinal plant that synthesizes such metabolites which include phenolic acids, carotenoids, quinones, antraquinones, flavonoids, flavonols, flavones, tannins, alkaloids, coumarins, terpenoids, amines, cyanogenic glycosides, triterpenoids, non-protein amino acids, glucosinolates, polyacetylenes, polyketides, phenylpropanes, steroids and saponins. They exert biological activities and can potentially be used to retard microbial activities. Other uses of M. oleifera are medicinal uses and other purposes such as water purification, fertilizer, biogas and biopesticides. The aim of this chapter is to highlight the uses and profiling of bio-active compounds of M. oleifera, their mode of action and prospects in commercial biopesticides for agricultural applications