945 research outputs found

    Lifestyle Intervention’s Effect and Predictive Value on Weight Loss for University Employees

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    Obesity is a costly and pervasive risk factor that requires attention to reduce chronic disease rates. This study evaluated the effect of a lifestyle medicine intervention, Complete Health Improvement Program (CHIP), on reducing weight, blood pressure, lipid levels, and hemoglobin A1c. A secondary aim was to build a preliminary predictive model for computing new participants’ potential weight change from CHIP. We evaluated pre- and post-intervention biometric data of 68 individuals who completed a 10-week CHIP intervention at a Midwestern university clinic. Significant reductions (p \u3c 0.05) were observed in weight, diastolic blood pressure, total cholesterol, low-density lipoprotein, and A1c. Regression analyses indicated that the best linear model for predicting change in weight was a one-predictor model with systolic blood pressure. The CHIP intervention effectively promoted weight loss and meaningful reductions in chronic disease risk factors. Larger samples are needed for future regression analyses to create a more robust linear model

    Malignant hypertension and acute aortic dissection associated with caffeine-based ephedra-free dietary supplements: a case report

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    The use of weight loss dietary supplements is prevalent in the United States, and over the past decade, there has been tremendous growth of the use of these products. It is well documented that ephedra-based products are associated with various cardiovascular adverse effects. With new restrictions placed on such products, companies are now manufacturing caffeine-based ephedra-free herbal supplements. We present the case of 36-year old, previously healthy female who developed malignant hypertension and aortic dissection while taking various caffeine-based dietary supplements. Given the lack of research studies in regards to their safety and efficacy, judicious care should be taken with the use of dietary supplements, including those designated as ephedra-free

    Battery energy storage system sizing using PSO algorithm in DIgSILENT powerfactory

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    The usage of battery energy storage system (BESS) can be a significant technology to improve the performance of power systems. Optimal sizing of BESS can reduce power losses, improve voltage profile and relieve peak demand in power systems. This paper aims to establish a simulation-based optimization in DIgSILENT Programming Language (DPL) script in DIgSILENT PowerFactory environment, which is more efficient for data exchange between operations. Problem for optimization of BESS sizing and placement are formulated in DPL script with analytic algorithm and particle swarm optimization (PSO) with loadflow simulation. The IEEE 9-bus system is the test case used to demonstrate and discuss the application of algorithms in DPL script. The placement of BESS is identified to be optimal with lowest power losses of 4.962 MW at bus 5 and the optimal BESS size of 47.168 MW with operation cost of 4852.65 $/h are determined. The output of the study concludes that optimal sizing of BESS can be applied in solving power system problems effectively with DPL operations. This paper serves as a reference for researchers to study and implement optimization approach in DIgSILENT DPL script

    P and T Odd Asymmetries in Lepton Flavor Violating Tau Decays

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    We calculated the differential cross sections of the processes in which one of the pair created tau particles at an e^+ e^- collider decays into lepton flavor violating final states e.g. tau -> mu gamma, tau -> 3 mu, tau -> mu ee. Using the correlations between angular distributions of both sides of tau decays, we can obtain information on parity and CP violations of lepton flavor non-conserving interactions. The formulae derived here are useful in distinguishing different models, since each model of physics beyond the standard model predicts different angular correlations. We also calculate angular distributions of the major background process to tau -> l gamma search, namely tau -> l nu \bar{\nu} gamma, and discuss usefulness of the angular correlation for background suppression.Comment: 31 pages, 5 figure

    Oral Pathobiont Activates Anti-Apoptotic Pathway, Promoting both Immune Suppression and Oncogenic Cell Proliferation.

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    Chronic periodontitis (CP) is a microbial dysbiotic disease linked to increased risk of oral squamous cell carcinomas (OSCCs). To address the underlying mechanisms, mouse and human cell infection models and human biopsy samples were employed. We show that the \u27keystone\u27 pathogen Porphyromonas gingivalis, disrupts immune surveillance by generating myeloid-derived dendritic suppressor cells (MDDSCs) from monocytes. MDDSCs inhibit CTLs and induce FOXP3 + 

    Observation of the Ωc0\Omega_{c}^{0} Charmed Baryon at CLEO

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    The CLEO experiment at the CESR collider has used 13.7 fb−1^{-1} of data to search for the production of the Ωc0\Omega_c^0 (css-ground state) in e+e−e^{+}e^{-} collisions at s≃10.6\sqrt{s} \simeq 10.6 {\rm GeV}. The modes used to study the Ωc0\Omega_c^0 are Ω−π+\Omega^- \pi^+, Ω−π+π0\Omega^- \pi^+ \pi^0, Ξ−K−pi+π+\Xi^- K^- pi^+ \pi^+, Ξ0K−pi+\Xi^0 K^- pi^+, and Ω−π+π−π+\Omega^- \pi^+ \pi^- \pi^+. We observe a signal of 40.4±\pm9.0(stat) events at a mass of 2694.6±\pm2.6(stat)±\pm1.9(syst) {\rm MeV/c2c^2}, for all modes combined.Comment: 10 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN

    Observation of B→ϕKB\to \phi K and B→ϕK∗B\to \phi K^{*}

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    We have studied two-body charmless hadronic decays of BB mesons into the final states phi K and phi K^*. Using 9.7 million BBˉB\bar{B} pairs collected with the CLEO II detector, we observe the decays B- -> phi K- and B0 -> phi K*0 with the following branching fractions: BR(B- -> phi K-)=(5.5 +2.1-1.8 +- 0.6) x 10^{-6} and BR(B0 -> phi K*0)=(11.5 +4.5-3.7 +1.8-1.7) x 10^{-6}. We also see evidence for the decays B0 -> phi K0 and B- -> phi K*-. However, since the statistical significance is not overwhelming for these modes we determine upper limits of <12.3 x 10^{-6} and <22.5 x 10^{-6} (90% C.L.) respectively.Comment: 9 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN

    Evidence of New States Decaying into Ξc′π\Xi^{\prime}_{c}\pi

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    Using 13.7 fb−1fb^{-1} of data recorded by the CLEO detector at CESR, we report evidence for two new charmed baryons: one decaying into Ξc0′π+\Xi_c^{0 \prime}\pi^+ with the subsequent decay Ξc0′→Ξc0γ\Xi_c^{0 \prime} \to \Xi_c^0 \gamma, and its isospin partner decaying into Ξc+′π−\Xi_c^{+ \prime} \pi^- followed by Ξc+′→Ξc+γ\Xi_c^{+\prime} \to \Xi_c^+\gamma. We measure the following mass differences for the two states: M(Ξc0γπ+)−M(Ξc0)M(\Xi_c^0 \gamma \pi^+)-M(\Xi_c^0)=318.2+-1.3+-2.9 MeV, and M(Ξc+γπ−)−M(Ξc+)M(\Xi_c^+ \gamma \pi^-)-M(\Xi_c^+)=324.0+-1.3+-3.0 MeV. We interpret these new states as the JP=1/2−Ξc1J^P = 1/2^- \Xi_{c1} particles, the charmed-strange analogs of the Λc1+(2593)\Lambda_{c1}^+(2593).Comment: 10 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN

    Measurement of the Relative Branching Fraction of Υ(4S)\Upsilon(4S) to Charged and Neutral B-Meson Pairs

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    We analyze 9.7 x 10^6 B\bar{B}$ pairs recorded with the CLEO detector to determine the production ratio of charged to neutral B-meson pairs produced at the Y(4S) resonance. We measure the rates for B^0 -> J/psi K^{(*)0} and B^+ -> J/psi K^{(*)+} decays and use the world-average B-meson lifetime ratio to extract the relative widths f+-/f00 = Gamma(Y(4S) -> B+B-)/Gamma(Y(4S) -> B0\bar{B0}) = = 1.04 +/- 0.07(stat) +/- 0.04(syst). With the assumption that f+- + f00 = 1, we obtain f00 = 0.49 +/- 0.02(stat) +/- 0.01(syst) and f+- = 0.51 +/- 0.02(stat) +/- 0.01(syst). This production ratio and its uncertainty apply to all exclusive B-meson branching fractions measured at the Y(4S) resonance.Comment: 11 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN

    First Observation of the Decays B0→D∗−ppˉπ+B^{0}\to D^{*-}p\bar{p}\pi^{+} and B^{0}\to D^{*-}p\bar{n}$

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    We report the first observation of exclusive decays of the type B to D^* N anti-N X, where N is a nucleon. Using a sample of 9.7 times 10^{6} B-Bbar pairs collected with the CLEO detector operating at the Cornell Electron Storage Ring, we measure the branching fractions B(B^0 \to D^{*-} proton antiproton \pi^+) = ({6.5}^{+1.3}_{-1.2} +- 1.0) \times 10^{-4} and B(B^0 \to D^{*-} proton antineutron) = ({14.5}^{+3.4}_{-3.0} +- 2.7) times 10^{-4}. Antineutrons are identified by their annihilation in the CsI electromagnetic calorimeter.Comment: 9 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN
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