A randomized controlled trial of an online, compassion-based intervention for maternal psychological well-being in the first year postpartum

Objectives New self-help interventions have been called for to promote psychological well-being amongst mothers in the first year postpartum, with compassion-based interventions having potential in this regard. The present study developed and evaluated a low-intensity, online, compassion-based intervention for this population called Kindness for Mums Online (KFMO). Methods UK mothers of infants under one year (N = 206) participated in a pragmatic randomized controlled trial, comparing KFMO with a waitlist control. Results The effect of the intervention on well-being (the primary outcome) was small and was sensitive to the way missing data were treated. However, KFMO robustly increased self-compassion relative to control, from baseline (week 0) to post-intervention (week 6), and from baseline to follow-up (week 12). No effects were observed on other secondary outcomes. Conclusions The findings suggest that self-compassion can be increased in postpartum mothers via an accessible, low-intensity, web-based, self-help program. However, this did not translate into robust improvements in well-being. Study limitations include relatively high attrition rates and limited generalizability to more diverse samples

Clinical trials update: endocrine and biological therapy combinations in the treatment of breast cancer

A greater understanding of the biological mechanisms responsible for de novo and acquired endocrine resistance has led to the rational design of clinical trials exploring the benefit of combining hormonal therapies with novel biological agents in an effort to enhance the efficacy of ER+ breast cancer treatment. These studies are increasingly including parallel biological analyses to elucidate the molecular characteristics of those tumors that are most likely to respond to specific targeted/endocrine combinations in an effort to develop a tailored approach to the management of individual patients. Unfortunately despite encouraging preclinical data, some of these combinations have yielded disappointing results in the clinical setting. This article will review the results of clinical trials of endocrine/biological combinations conducted in early and advanced breast cancer as well as provide an update on ongoing studies

Measuring competitive self-focus perspective taking, submissive compassion and compassion goals.

Research in the last 20 years has provided good evidence that developing compassion-focused motives for self and others has a range of benefits. However, people can behave in prosocial ways for different reasons, not all of which are genuinely care focused. This paper reports research comparing submissive compassion (being helpful to be liked) to “genuine” compassion in relation to domains of empathy and perspective taking. We developed a new short (5 item) self-report scale (the competitive perspective taking scale) to explore how people might use perspective taking for self-focused reasons. We investigated its association with validated empathy and compassion measures.N/

Gilt Dragons, porcelain and plundered doubloons: A comparative analysis of Taiwan and Australian underwater cultural heritage protection laws

Taiwan and Australia are non-Parties to the UNESCO Convention on the Protection of the Underwater Cultural Heritage (UCH Convention). However, as the first two non-Parties in the East Asia region, both have incorporated the spirit and letter of the UCH Convention into their respective domestic laws, with minor exceptions to fit into their respective historical and cultural contexts, as well as their administrative and judicial settings. This paper traces and compares the very different origins of these two pieces of UCH specific domestic legislation. A comparative analysis is also made of the structure and content, similarities and differences of each piece of legislation as well as deviations between them and between the UCH Convention. The paper argues that the Taiwanese and Australian experience demonstrates models for the successful incorporation of the UCH Convention for States striving for the preservation, protection and management of UCH

Ultrasound diagnosis of evolving pyloric stenosis

Two infants with recurrent episodes of vomiting had upper gastrointestinal barium studies that did not show radiographic features of pyloric stenosis. However, follow-up abdominal sonograms done 1–2 weeks later documented hypertrophic pyloric stenosis, which led to surgery. This entity is not congenital, but an evolving acquired lesion. Therefore, ultrasound is an excellent modality to evaluate and monitor patients clinically suspected of developing hypertrophic pyloric stenosis despite their initially negative imaging studies.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/48137/1/261_2005_Article_BF01889148.pd