9 research outputs found

    Efficient synthesis of novel polyfunctionalised 4,5'-bithiazol-4'-ol derivatives

    No full text
    2-Thiazolin-4-one derivatives, obtained by reaction of tert-butyl (3-methoxy-1-methyl-3-oxoprop-1-enyl)diazenecarboxylate with aryl thioamides, were transformed into 5-bromoacetyl-4-hydroxythiazole derivatives by polymer-supported reagents and simple work-up procedures. The compounds thus synthesised were coupled with thioamides bearing valuable functional groups affording novel polyfunctionalised 4,5\u2032-bithiazol-4\u2032-ol derivative
    corecore