A SimRank based Ensemble Method for Resolving Challenges of Partition Clustering Methods

323–327Traditional clustering techniques alone cannot resolve all challenges of partition-based clustering methods. In the partition based clustering, particularly in variants of K-means, initial cluster centre selection is a significant and crucial point. The dependency of final cluster is totally based on initial cluster centres; hence, this process is delineated to be most significant in the entire clustering operation. The random selection of initial cluster centres is unstable, since different cluster centre points are achieved during each run of the algorithm. Ensemble based clustering methods resolve challenges of partition-based methods. The clustering ensembles join several partitions generated by different clustering algorithms into a single clustering solution. The proposed ensemble methodology resolves initial centroid problems and improves the efficiency of cluster results. This method finds centroid selection through overall mean distance measure. The SimRank based similarity matrix find that the bipartite graph helps to ensemble

A SimRank based Ensemble Method for Resolving Challenges of Partition Clustering Methods

Traditional clustering techniques alone cannot resolve all challenges of partition-based clustering methods. In the partition based clustering, particularly in variants of K-means, initial cluster centre selection is a significant and crucial point. The dependency of final cluster is totally based on initial cluster centres; hence, this process is delineated to be most significant in the entire clustering operation. The random selection of initial cluster centres is unstable, since different cluster centre points are achieved during each run of the algorithm. Ensemble based clustering methods resolve challenges of partition-based methods. The clustering ensembles join several partitions generated by different clustering algorithms into a single clustering solution. The proposed ensemble methodology resolves initial centroid problems and improves the efficiency of cluster results. This method finds centroid selection through overall mean distance measure. The SimRank based similarity matrix find that the bipartite graph helps to ensemble

Case report on renal failure reversal in lambda chain multiple myeloma with bortezomib and dexamethasone

Renal failure (RF) reversal in multiple myeloma (MM) is associated with an improved prognosis. Light chain myeloma, serum creatinine (SCr) \u3e 4 mg/dL, extensive proteinuria, early infections, and certain renal biopsy findings are associated with lower rates of RF reversal. Our patient is a 67-year-old female with multiple poor prognostic factors for RF reversal who demonstrated a rapid renal response with bortezomib and dexamethasone (BD) regimen. She presented initially with altered mental status. On exam, she appeared lethargic and dehydrated and had generalized tenderness. She had been taking ibuprofen as needed for pain for a few weeks. Labs showed a white cell count-18,900/muL with no bandemia, hemoglobin 10.8 gm/dL, potassium-6.7 mEq/L, bicarbonate-15 mEq/L, blood urea nitrogen-62 mg/dL, SCr-5.6 mg/dL (baseline: 1.10), and corrected calcium-11.8 mg/dL. A rapid flu test was positive. Imaging studies were unremarkable. Her EKG showed sinus tachycardia and her urinalysis was unremarkable. The unexplained RF in an elderly individual in conjunction with hypercalcemia and anemia prompted a MM work-up; eventually, lambda variant MM was diagnosed. An immediate (4 days) renal response defined as 50% reduction in SCr was noticed after initiation of the BD regimen

How hybrids manage growth and social–business tensions in global supply chains: the case of impact sourcing

This study contributes to the growing interest in how hybrid organizations manage paradoxical social–business tensions. Our empirical case is ‘‘impact sourcing’’— hybrids in global supply chains that hire staff from disadvantaged communities to provide services to business clients. We identify two major growth orientations— ‘‘community-focused’’ and ‘‘client-focused’’ growth—their inherent tensions and ways that hybrids manage them. The former favors slow growth and manages tensions through highly integrated client and community relations; the latter promotes faster growth and manages client and community relations separately. Both growth orientations address social–business tensions in particular ways, but also create latent constraints that manifest when entrepreneurial aspirations conflict with the current growth path. In presenting and discussing our findings, we introduce preempting management practices of tensions, and the importance of geographic embeddedness and distance to the paradox literature

Opening up to foreign competition : an analysis of Indian durable consumer goods industry

We examine the most likely strategy of product differentiation by newly entering multinational firms when market reforms begin in a developing economy. We argue that incumbents in a non-contestable protected market do not have the usual advantages of an incumbent as in a standard sequential entry model of contestable markets. In this context we use a model of vertical product differentiation to argue that a new entrant will choose a higher quality product and a higher price given the income distribution profile brought in by the market reforms. We test the propositions empirically on the basis of firm level panel data for five Indian durable consumer goods industries

Policy Reforms and Evolution of Market Structure in an Emerging Economy: The Case of India

Policy reforms have facilitated entry of quite a few transnational corporations (TNC) into Indian industries. This has important implications for the evolution of competitive industrial structure. This article focuses on the issue of the response mechanism of local firms to competition from new entrant TNCs and the possible strategies of TNCs in penetrating the Indian market. It develops a conceptual framework by incorporating elements of intangible assets theory and new institutional economics into a simple sequential entry oligopoly model. This yields interesting insights into qualitative behaviour of firms in the post-reforms period. A few hypotheses drawn from the conceptual framework are empirically tested on the basis of firm level panel data drawn from a set of Indian industries.market reforms, transnational corporations, incumbent local firms, new entrants and market institutions,