6 research outputs found
Sex: A change in our guidelines to authors to ensure that this is no longer an ignored experimental variable.
A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research
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A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: reproducibility of natural product research
Conclusions
This editorial illustrates major requirements that authors should con- sider before submitting articles to BJP (see Table 3 for authors' check- list). It also highlights some common shortcomings in natural product pharmacological research, which could be prevented if experiments have appropriate planning and experimental design.
BJP is a leading journal in the pharmacological field, in which important new advances are published, and thus, novelty is a major determinant of acceptance for publication. Studies showing the effect of natural products, without a substantial investigation into the mode of action, are not considered. Articles limited to repetition of well- known data or that report similar pharmacological activities of similar chemical compounds are generally not suitable for BJP.
The editors of BJP recognize the wealth of opportunity for thera- peutics that comes from the natural world and are keen to publish excellent natural product pharmacology that advances understanding of mechanisms of both physiological and pathological processes or that identifies potential new therapeutics
Recommended from our members
Sex: a change in our guidelines to authors to ensure that this is no longer an ignored experimental variable
Summary
• BJP now requires sex to be considered as an experimental variable for all experimental reporting. This will affect the details of the experimental design that are documented or, in the absence of a design incorporating both sexes, a full justification for that approach.
• We recommend that all experiments (in vitro, in vivo, and ex vivo) should include both sexes, unless there is a specific justification or exemption, such as when using immortalised cell lines or tissue derived from a sex organ.
• Multifactorial designs should be used to study the overall effects of Sex, Treatment (i.e., the experimental intervention), and their interaction.
• Authors should consider the implications for the study findings when testing males and females in close proximity, particularly in behavioural studies, and describe these implications in the discus- sion of the manuscript